Cancer targeted therapies have become increasingly prevalent in recent years. Epidemiological studies indicate a significant rise in the number of patients receiving targeted therapies, particularly in certain cancer types such as lung and colorectal cancers, where the proportion of patients treated with targeted drugs has increased by approximately 20-30% over the past decade. Nutrition plays a critical role in cancer patients undergoing targeted therapy. Adequate nutritional status is essential for optimizing the efficacy of targeted treatments. Proper nutrition can improve patients' ability to tolerate therapies, reduce the occurrence of adverse effects, and enhance quality of life throughout treatment. Furthermore, appropriate nutritional support strengthens immune function, which can positively impact long-term survival and recovery outcomes.

Nevertheless, the issue of malnutrition in cancer patients undergoing targeted therapy has often been overlooked. The mechanisms through which nutritional status influences the efficacy of cancer treatments remain poorly understood, contributing to suboptimal clinical outcomes. This knowledge gap highlights the urgent need for further research to better understand the relationship between nutrition and treatment effectiveness in these patients.

This Research Topic aims to delve into the intricate effects of nutrition on the efficacy of targeted therapies in cancer treatment. Our objectives focus on elucidating the mechanisms by which nutrition impacts therapy responses and patient health, ultimately aiming to enhance both treatment effectiveness and patient quality of life.

This Research Topic welcomes original research including, but not limited to, the following areas:
• The mechanisms through which malnutrition impact the efficacy of targeted therapies in cancer patients.
• Correlations between nutritional statuses (indicators) and the effectiveness of targeted drugs, especially using large-scale epidemiological studies.
• The influence of specific nutritional indicators on predicting treatment outcomes and patient prognoses.
• Development of prognostic models that incorporate nutritional markers.
• The role of specialized nutritional support (such as foods for special medical purposes or nutritional formulations) in improving response to cancer therapy.
• Tools for screening and assessing malnutrition in cancer treatment contexts.
• Nutrition-related patient-reported outcomes (PROS) in antitumor therapy
• Clinical studies and mechanisms on how gut microbiota-modifying agents can enhance anti-cancer treatment efficacy.

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Frontiers in Nutrition

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