It is well known that selenium is an essential trace element in the human body and plays an important role in human health. Over 40 serious diseases are highly associated with selenium deficiency, including Keshan disease, Kashin Beck disease, arthritis, liver injury, cancer, diabetes, cataracts, hyperglycemia, and so on. However, long-term excessive selenium intake will also cause skin damage, hair and nail loss. Its biological activity and toxicity are closely related to selenium content, selenium species, dietary patterns, and so on. Therefore, the research on selenium and human health is of great significance.

To the best of our knowledge, it still lacks a final consensus on whether human beings need the supplement of selenium, even people who live in selenium-deficiency districts. On the one hand, some searchers claimed that the occurrence of many serious diseases in living beings was closely related to selenium deficiency, selenium supplements can cure or alleviate the diseases. On the other hand, some researchers indicated that no convincing evidence proved selenium deficiency led to the formation of the diseases. Furthermore, selenium, especially inorganic selenium, has a very narrow range of safe intake, overdose addition in foods may lead to serious consequences. Thus, cutting-edge research about the effects and mechanisms of selenium on food quality, synergism or antagonism with other nutrients and human health are advantageous to tackle the above contradiction.

People around the world still lack an incisive and unified understanding of the impact of selenium on human health. This Research Topic aims to contribute to the latest knowledge about Selenium and Human health by presenting the effects and mechanisms of inorganic selenium, organic selenium, and nano-selenium on the quality of different foods, synergism or antagonism with other nutrients and human health. We hope that more consensuses on the impact of selenium on human health can be obtained and the latest relevant research can be widely spread via this research topic, and hope that the research topic can contribute to promoting human health.

Sub-themes for this Research Topic may include, but are not limited to:
1. Effects and the related mechanisms of inorganic selenium, organic selenium and nano-selenium on the food quality.
2. Effects of different selenium-rich foods on human health (or model animals) and the related mechanisms.
3. The production technologies of new selenium-rich foods and the changes and metabolism pathways of selenium during processing.
4. Bioavailability, bioactivity and toxicity of different selenium species in humans.
5. Synergism or antagonism mechanism of selenium with other nutrients in the metabolic regulation.
6. Other latest studies related to selenium and human nutrition.

Submit your idea

Impact

Frontiers in Nutrition

Participating Journals

Impact