About this Research Topic
Ruminant viral diseases pose a significant threat to global agriculture, particularly impacting the cattle and sheep industries. These diseases are not only harmful and highly contagious but can also render entire farms or regions vulnerable to outbreaks. Importantly, the existence of viruses such as Bovine Parainfluenza Virus type 3 (BPIV-3), Bovine Rhinitis B Virus (BRBV), Bovine Viral Diarrhea Virus (BVDV), Peste des Petits Ruminants Virus (PPRV), Akabane virus (AKAV), and Rotavirus (RV) acknowledges several issues. These pathogens have shown capabilities of mutation and recombination, further aggravated by the enhanced virus dispersal linked to increased international trade. This continuous viral evolution undermines existing immunoprevention strategies, representing a growing challenge in the control and economic stability of the livestock industry at a global scale.
This Research Topic is designed to consolidate the most recent, high-quality findings on the pathogenesis of key viral diseases in ruminants. By focusing on epidemiological research, the mechanisms of disease onset, and immune escape, along with the development of new vaccines related to disease prevention and control, we aim to lay a robust foundation for the advancement of novel antiviral drugs and strategies. This compilation will foster a comprehensive understanding of current challenges and facilitate the dissemination of innovative research findings among the scientific community.
This scope ensures a comprehensive exploration of the challenges and strategies in managing ruminant viral diseases, aimed at enhancing public and animal health outcomes.
These adjustments refine the proposal to be clear, concise, and to meet the requirements laid out in your initial document, focusing academically on the scientific advancements needed in the field. To address this complex and evolving threat adequately, the Research Topic will cover a spectrum of thematic areas including:
o Genetic evolution: Understand the genetic modifications in viruses over time and their implications on disease dynamics.
o Testing techniques: Develop and refine methods for effective detection and analysis of viruses in ruminant populations.
o Immune evasion mechanisms: Examine how viruses circumvent host immune defenses, contributing to their persistence and spread.
o Protein-protein interactions: Investigate interactions between viral and host proteins that influence disease manifestation and progression.
o Vaccine creation: Focus on the innovation and evaluation of new vaccines that could lead to effective prevention strategies.
This Research Topic is designed to consolidate the most recent, high-quality findings on the pathogenesis of key viral diseases in ruminants. By focusing on epidemiological research, the mechanisms of disease onset, and immune escape, along with the development of new vaccines related to disease prevention and control, we aim to lay a robust foundation for the advancement of novel antiviral drugs and strategies. This compilation will foster a comprehensive understanding of current challenges and facilitate the dissemination of innovative research findings among the scientific community.
This scope ensures a comprehensive exploration of the challenges and strategies in managing ruminant viral diseases, aimed at enhancing public and animal health outcomes.
These adjustments refine the proposal to be clear, concise, and to meet the requirements laid out in your initial document, focusing academically on the scientific advancements needed in the field. To address this complex and evolving threat adequately, the Research Topic will cover a spectrum of thematic areas including:
o Genetic evolution: Understand the genetic modifications in viruses over time and their implications on disease dynamics.
o Testing techniques: Develop and refine methods for effective detection and analysis of viruses in ruminant populations.
o Immune evasion mechanisms: Examine how viruses circumvent host immune defenses, contributing to their persistence and spread.
o Protein-protein interactions: Investigate interactions between viral and host proteins that influence disease manifestation and progression.
o Vaccine creation: Focus on the innovation and evaluation of new vaccines that could lead to effective prevention strategies.
Keywords: Ruminant, Virus, Pathogenesis, Cattle, Sheep
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
