About this Research Topic
In the realm of renal transplantation, distinguishing the disparities between pediatric and adult procedures remains a pressing concern. The complexities that underpin these differences range from donor selection and immunological challenges to the administration and response to immunosuppressive treatments. Moreover, clinical outcomes and complications vary significantly across age groups. The critical transition from pediatric to adult healthcare intricately influences regimen adherence and broader social outcomes, including educational attainment, employment status, relationship quality, life satisfaction, and mental health.
This Research Topic aims to explore into the multifaceted aspects of renal transplants for both children and adults to enhance understanding and improve care provisions. Addressing the underlying differences in donor compatibility, immunosuppressive strategies, risk of rejection, and complication management are pivotal. Additionally, the Topic will explore the period of transition care, crucial in safeguarding continuity and support for young patients and their families as they shift to adult care settings.
To gather further insights in this crossover of pediatric and adult transplantation care, we welcome articles addressing, but not limited to, the following themes:
· Donor selection and HLA compatibility requirements in the different age groups
· Surgical challenges in pediatric versus adult transplantation
· Graft rejection in children versus adult recipients: from the fundamental research to the clinical data
· Differences in immunosuppressive regimens, focusing on m-TOR inhibitors
· Management and implications of Epstein-Barr and other viruses
· The burden of urinary tract infections in transplanted recipients
· Challenges in transitioning from pediatric to adult care for teenagers and young adults
· Long-term health outcomes such as graft survival, complications, and mortality
· The psycho-social impacts of transplantation performed at different ages
This Research Topic aims to explore into the multifaceted aspects of renal transplants for both children and adults to enhance understanding and improve care provisions. Addressing the underlying differences in donor compatibility, immunosuppressive strategies, risk of rejection, and complication management are pivotal. Additionally, the Topic will explore the period of transition care, crucial in safeguarding continuity and support for young patients and their families as they shift to adult care settings.
To gather further insights in this crossover of pediatric and adult transplantation care, we welcome articles addressing, but not limited to, the following themes:
· Donor selection and HLA compatibility requirements in the different age groups
· Surgical challenges in pediatric versus adult transplantation
· Graft rejection in children versus adult recipients: from the fundamental research to the clinical data
· Differences in immunosuppressive regimens, focusing on m-TOR inhibitors
· Management and implications of Epstein-Barr and other viruses
· The burden of urinary tract infections in transplanted recipients
· Challenges in transitioning from pediatric to adult care for teenagers and young adults
· Long-term health outcomes such as graft survival, complications, and mortality
· The psycho-social impacts of transplantation performed at different ages
Keywords: kidney tranplantation, children, adults, transplant recipients, graft survival
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
