About this Research Topic
Bioactive compounds derived from natural sources have been utilized in traditional medicine for centuries due to being known for their therapeutic effects in treating various ailments. Recent scientific advancements have allowed for a more comprehensive understanding of these compounds, especially their interactions with regulatory pathways and hormones relevant to endocrinology. Studies have revealed that these naturally occurring substances can influence key endocrine functions, such as insulin production, thyroid regulation, and reproductive health. Their pharmacological potential, including their impact on hormone modulation, is gaining interest in modern therapeutic approaches. Despite this progress, the full clinical potential of these compounds remains underexplored, especially concerning their pharmacokinetics, bioavailability, and long-term efficacy in treating endocrine disorders like diabetes, obesity, and thyroid-related conditions.
This article collection aims to bridge the knowledge gap by investigating the molecular mechanisms and clinical applications of naturally occurring bioactive compounds in endocrinology. It will explore how these compounds influence key hormonal pathways and their potential as therapeutic agents for managing endocrine disorders. By focusing on their pharmacokinetics, bioavailability, and combination with existing therapies, the collection seeks to provide a deeper understanding of their efficacy and safety in clinical settings. The articles will address challenges such as optimizing bioavailability, understanding metabolism, and assessing the long-term impact of phytochemicals on endocrine function. This research topic aims to highlight innovative approaches, from basic molecular studies to clinical trials, contributing to the better management of endocrine diseases.
Authors are invited to submit manuscripts addressing, but not limited to the following areas:
- Molecular Mechanisms of Phytochemicals in Endocrinology: Investigate how natural compounds influence hormonal pathways, including insulin production, glucagon regulation, thyroid function, and stress hormone responses.
- Pharmacokinetics and Bioavailability of Natural Products: Explore the absorption, distribution, metabolism, and elimination (ADME) of phytochemicals and their potential as regulators of endocrine functions.
- Endocrine Regulation through Phytochemicals: Focus on the modulation of endocrine pathways by natural products, particularly in insulin sensitivity, thyroid hormone balance, and metabolic processes.
- Combination Therapies with Phytochemicals: Examine the potential of phytochemicals to enhance the efficacy of conventional endocrine therapies through synergistic effects.
- Phytochemicals in Metabolism and Reproductive Health: Study the effects of natural compounds on metabolism, fat regulation, appetite control, and their influence on reproductive hormones, including PCOS and menopause management
**For manuscripts submitted to Frontiers in Pharmacology: Studies need to comply with the best practice guidelines of the leading journals for pharmacological studies on plant extract / natural products including the Four Pillars of Best Practice in Ethnopharmacology including a detailed description of the material studied, its extraction and processing. You can freely download the full version here. Please self-assess your MS using the ConPhyMP tool, and follow the standards established in the ConPhyMP statement Front. Pharmacol. 13:953205.
This article collection aims to bridge the knowledge gap by investigating the molecular mechanisms and clinical applications of naturally occurring bioactive compounds in endocrinology. It will explore how these compounds influence key hormonal pathways and their potential as therapeutic agents for managing endocrine disorders. By focusing on their pharmacokinetics, bioavailability, and combination with existing therapies, the collection seeks to provide a deeper understanding of their efficacy and safety in clinical settings. The articles will address challenges such as optimizing bioavailability, understanding metabolism, and assessing the long-term impact of phytochemicals on endocrine function. This research topic aims to highlight innovative approaches, from basic molecular studies to clinical trials, contributing to the better management of endocrine diseases.
Authors are invited to submit manuscripts addressing, but not limited to the following areas:
- Molecular Mechanisms of Phytochemicals in Endocrinology: Investigate how natural compounds influence hormonal pathways, including insulin production, glucagon regulation, thyroid function, and stress hormone responses.
- Pharmacokinetics and Bioavailability of Natural Products: Explore the absorption, distribution, metabolism, and elimination (ADME) of phytochemicals and their potential as regulators of endocrine functions.
- Endocrine Regulation through Phytochemicals: Focus on the modulation of endocrine pathways by natural products, particularly in insulin sensitivity, thyroid hormone balance, and metabolic processes.
- Combination Therapies with Phytochemicals: Examine the potential of phytochemicals to enhance the efficacy of conventional endocrine therapies through synergistic effects.
- Phytochemicals in Metabolism and Reproductive Health: Study the effects of natural compounds on metabolism, fat regulation, appetite control, and their influence on reproductive hormones, including PCOS and menopause management
**For manuscripts submitted to Frontiers in Pharmacology: Studies need to comply with the best practice guidelines of the leading journals for pharmacological studies on plant extract / natural products including the Four Pillars of Best Practice in Ethnopharmacology including a detailed description of the material studied, its extraction and processing. You can freely download the full version here. Please self-assess your MS using the ConPhyMP tool, and follow the standards established in the ConPhyMP statement Front. Pharmacol. 13:953205.
Keywords: Metabolism, Natural, Phytochemicals, Bioactive, Medicine, Hormones
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
