About this Research Topic
Some patients who had COVID-19 subsequently develop long-COVID syndrome or/and post-COVID syndrome. In long-COVID syndrome (time span 4 weeks to three months after COVID-19) it has been found that during this time window, a multitude of symptoms can emerge that are unrelated to the initial manifestations of COVID-19. These often include unspecific neurological symptoms like fatigue, irritability, and mnestic problems. Also, in post-COVID syndrome (time span three months to years after COVID-19) there is persistence or new emergence of symptoms related to SARS-CoV-2. Long-COVID syndrome as well as post-COVID syndrome are still incompletely understood regarding their pathological, molecular, and immunological basis. The patients often describe neuropsychological deterioration. A typical neurological manifestation during this time window is fatigue with varying degrees. The condition is clinically similar to chronic fatigue syndrome, also named myalgic encephalomyelitis.
With this research topic, we aim for a better insight into the cellular and molecular mechanisms of the causes of long-COVID and post-COVID syndromes. So far, there are few treatments of variable efficacy for long-COVID and post-COVID syndromes. It is of paramount importance to find and implement novel treatment approaches. In addition, it would be of interest to define co-factors (genetics, environmental) that predispose to the emergence of long-COVID and post-COVID syndromes.
All types of articles can be submitted to this research topic and we are most interested in original articles with original research data. We are interested in the following content:
• Immunological basis of long-COVID and post-COVID syndromes.
• Immunological signatures associated with long-COVID and post-COVID syndromes.
• Genetic and environmental factors that predispose in the context of COVID-19 to long-COVID and post-COVID syndromes.
• Treatment approaches for long-COVID and post-COVID syndromes.
• Clinical studies with patients with long-COVID and post-COVID syndromes.
• Studies demonstrating the immunological similarities or/and disparities of post-COVID syndrome and chronic fatigue syndrome, also named myalgic encephalomyelitis.
With this research topic, we aim for a better insight into the cellular and molecular mechanisms of the causes of long-COVID and post-COVID syndromes. So far, there are few treatments of variable efficacy for long-COVID and post-COVID syndromes. It is of paramount importance to find and implement novel treatment approaches. In addition, it would be of interest to define co-factors (genetics, environmental) that predispose to the emergence of long-COVID and post-COVID syndromes.
All types of articles can be submitted to this research topic and we are most interested in original articles with original research data. We are interested in the following content:
• Immunological basis of long-COVID and post-COVID syndromes.
• Immunological signatures associated with long-COVID and post-COVID syndromes.
• Genetic and environmental factors that predispose in the context of COVID-19 to long-COVID and post-COVID syndromes.
• Treatment approaches for long-COVID and post-COVID syndromes.
• Clinical studies with patients with long-COVID and post-COVID syndromes.
• Studies demonstrating the immunological similarities or/and disparities of post-COVID syndrome and chronic fatigue syndrome, also named myalgic encephalomyelitis.
Keywords: Immunological basis, long-COVID, post-COVID syndromes, adaptive immunity, innate immunity, SARS-COV-2
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
