In the field of nephrology, glomerular diseases represent a critical area marked by diverse etiologies and complex pathophysiological mechanisms. Their impact on global health remains profound, as these diseases often lead to chronic kidney disease and end-stage kidney failure. The increasing prevalence and worsening outcomes highlight a persistent gap in effective diagnostic and therapeutic strategies. Great strides have been made in the field of glomerular diseases over past decade through advances in basic and translational research leading to discovery of novel antigens and better understanding of immunopathogenesis. There has been successful completion of clinical trial and newly approved and targeted therapies.

This Research Topic aims to deepen our understanding of glomerular diseases through comprehensive investigations into their pathogenesis, progression, and response to treatment. Specifically, it seeks to address critical questions regarding the underlying genetic predispositions, the role of the immune system in disease exacerbation, and the effectiveness of existing and emerging therapies. The goal is to identify novel biomarkers for early detection and to evaluate the efficacy of personalized treatment modalities that could significantly alter the disease trajectory and improve patient outcomes.
To gather further insights in this rapidly evolving field, we welcome articles addressing, but not limited to, the following themes:

Novel genetic and epigenetic factors contributing to glomerular disease susceptibility.

Advances in diagnostic technologies for early and accurate detection.

Immunological aspects of glomerular diseases and their therapeutic implications.

Clinical trials of new pharmacological treatments and their long-term impacts.

Comparative studies on the effectiveness of conventional versus emerging therapeutic strategies.

This detailed inquiry aims to bridge the gap between research and clinical application, fostering a deeper understanding that could lead to significant advancements in patient care for glomerular diseases.

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Frontiers in Nephrology

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