About this Research Topic
Nanotechnology has the potential to manipulate physical, chemical and biological properties of materials at the nanoscale, enabling unique properties such as high surface area-to-volume ratio, and advancing the application of materials for numerous biomedical purposes. Nanotechnology-processed materials may include a wide variety of materials such as polymeric matrixes, encapsulation, lipidic carriers, zero valent metallic nanoparticles, metal oxides and carbon nanostructures, which have numerous applications such as tissue regeneration, drug delivery, diagnostic aids, and bioimplants purposes. For instance, nanoparticles exhibit relatively higher surface area-to-volume ratio which leads to their more favourable surface interactions with biological macromolecules, enabling more precise targeting of disease sites, and prolonged duration of action, while nanometallic oxides, which includes zinc and titanium, have distinguished photocatalytic abilities to generate reactive oxygen species, which are harnessed for biomedical applications towards antimicrobial and anticancer treatments.
Recent research efforts have focused on investigating the effectiveness of nanomaterials for biomedical applications, for instance on developing novel strategies to improve targeting of disease sites, and to prolong their retention in pathological tissues to extend the duration action. These nanoparticles can be purposed for the application of producing high-resolution imaging, drug-resistance antimicrobial treatment, point of care biomedical devices, improving solubility of poorly bioavailable drugs and targeted delivery of loads in a rate-controlled manners. Materials at the nanoscale may have associated risks factors, owing to their unique properties. So, another important advancement in the field of nanotechnology includes investigating how surface characteristics and morphology can impact biological systems, developing strategies to continuously monitor them, and to assess potential risks so that adverse effects can be mitigated. This Research Topic will review advancements in nanotechnology for processing of materials, focusing on their safety and biomedical applications.
This Research Topic will explore advancements in different processes towards fabrication of nanotechnology-enabled materials for biomedical applications. The focus will also be towards different innovative tools and techniques to characterize properties and abilities of these nanomaterials, to harness their transformative potentials towards developing innovative solutions for diagnosis, bioimplants and drug delivery. Another scope of this Topic is to emphasize on progress made towards understanding their toxicology, essential to ensure the safe and effective use of these transformative materials.
In particular, this Topic will aim to explore the impact of different processing conditions over nanomaterials attributes, in terms of their dimension, morphology, physical characteristics, catalytic properties, biosensing abilities and biological interactions, investigating how these properties affect the role of nanomaterials in different biomedical applications such as drug release, duration of action, and clinical efficacy.
This Research Topic welcomes Original Research, Review, Mini-review, and Perspective articles covering topics related, but not limited to:
• Recent advancements and challenges associated with the use of nanomaterials for biomedical applications.
• Factors and processes affecting growth and assembling of materials at nanoscale levels.
• Impact of materials and processing conditions over the geometry and morphology of nanomaterials; affecting behaviors and biomedical responses.
• Techniques and tools for the characterization of nanomaterials for their mechanical, electrochemical, spectroscopic properties; their roles in imaging devices; enabling purposes in biomedical devices in terms of energy harvesting, bio-sensing, photonics, optoelectronics, genetic manipulations, and targeted delivery drugs at pathological sites.
• Assessment tools and understanding towards efficacy, safety and toxicity of nanoparticles and their products.
• In-silico modelling and optimization of processes for developing judicious strategies to predict characteristics and performances of the nanomaterial products.
• Strategies to adopt desired processing of nanotechnological tools, selection of appropriate materials, and characterizing their performances to fabricate nanomaterials with desired biomedical performance with assurances of their safety.
Recent research efforts have focused on investigating the effectiveness of nanomaterials for biomedical applications, for instance on developing novel strategies to improve targeting of disease sites, and to prolong their retention in pathological tissues to extend the duration action. These nanoparticles can be purposed for the application of producing high-resolution imaging, drug-resistance antimicrobial treatment, point of care biomedical devices, improving solubility of poorly bioavailable drugs and targeted delivery of loads in a rate-controlled manners. Materials at the nanoscale may have associated risks factors, owing to their unique properties. So, another important advancement in the field of nanotechnology includes investigating how surface characteristics and morphology can impact biological systems, developing strategies to continuously monitor them, and to assess potential risks so that adverse effects can be mitigated. This Research Topic will review advancements in nanotechnology for processing of materials, focusing on their safety and biomedical applications.
This Research Topic will explore advancements in different processes towards fabrication of nanotechnology-enabled materials for biomedical applications. The focus will also be towards different innovative tools and techniques to characterize properties and abilities of these nanomaterials, to harness their transformative potentials towards developing innovative solutions for diagnosis, bioimplants and drug delivery. Another scope of this Topic is to emphasize on progress made towards understanding their toxicology, essential to ensure the safe and effective use of these transformative materials.
In particular, this Topic will aim to explore the impact of different processing conditions over nanomaterials attributes, in terms of their dimension, morphology, physical characteristics, catalytic properties, biosensing abilities and biological interactions, investigating how these properties affect the role of nanomaterials in different biomedical applications such as drug release, duration of action, and clinical efficacy.
This Research Topic welcomes Original Research, Review, Mini-review, and Perspective articles covering topics related, but not limited to:
• Recent advancements and challenges associated with the use of nanomaterials for biomedical applications.
• Factors and processes affecting growth and assembling of materials at nanoscale levels.
• Impact of materials and processing conditions over the geometry and morphology of nanomaterials; affecting behaviors and biomedical responses.
• Techniques and tools for the characterization of nanomaterials for their mechanical, electrochemical, spectroscopic properties; their roles in imaging devices; enabling purposes in biomedical devices in terms of energy harvesting, bio-sensing, photonics, optoelectronics, genetic manipulations, and targeted delivery drugs at pathological sites.
• Assessment tools and understanding towards efficacy, safety and toxicity of nanoparticles and their products.
• In-silico modelling and optimization of processes for developing judicious strategies to predict characteristics and performances of the nanomaterial products.
• Strategies to adopt desired processing of nanotechnological tools, selection of appropriate materials, and characterizing their performances to fabricate nanomaterials with desired biomedical performance with assurances of their safety.
Keywords: nanotechnology, biosensors, drug delivery, gene therapy, imaging
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
