The field of clinical research on eye diseases has experienced an extraordinary surge in both quantity and quality, highlighting its vital role in contemporary medicine. This rapid growth is driven by the integration of advanced technologies, which have transformed traditional methodologies and introduced groundbreaking new concepts. From innovative diagnostic techniques to novel therapeutic strategies, these advancements have significantly improved patient outcomes, making eye disease research a pivotal area of medical exploration. Furthermore, clinical research in ophthalmology is increasingly adopting a more standardized and systematic approach. This evolution is crucial for ensuring the reproducibility and reliability of research findings, thereby enhancing their application in clinical practice. However, these advancements are accompanied by complex ethical challenges, such as issues related to patient consent, data privacy, and the equitable distribution of cutting-edge treatments. Addressing these ethical concerns is essential for the continued advancement of clinical research on eye diseases.

This research topic aims to provide a comprehensive platform for exploring and disseminating the latest advancements and future directions in the clinical research of eye diseases. Our goal is to foster further discussion and collaboration among researchers, driving the field forward. We aim to answer specific questions related to novel approaches and applications in clinical research, including new interpretations and methodologies, biomarkers for early diagnosis and prognosis, and the integration of artificial intelligence with clinical research.

To gather further insights in the clinical research of eye diseases, we welcome articles addressing, but not limited to, the following themes:
- Cornea and external disease
- Cataract and refractive surgery
- Glaucoma
- Retinal disease
- Ocular immunology and uveitis
- Neuro-ophthalmology
- Pediatric ophthalmology and strabismus
- Ocular oncology
- Oculoplastic and orbital surgery
- Refractive error and visual rehabilitation

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Frontiers in Medicine

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