In the continuously advancing field of genetics, particularly within human and medical genomics, the last ten years have seen an array of significant achievements and breakthroughs. These developments have redefined our understanding of genetic factors in health and disease, opening new pathways for therapeutics and diagnostics.

Frontiers has organized a series of Research Topics to highlight the latest advancements in research across the field of genetics, with articles from the members of our accomplished Editorial Boards and the broader research community. This Research Topic series focuses on new insights, developments, challenges, latest discoveries, recent advances, and future perspectives in the field of human and medical genomics. Led by Dr. Jared Roach and Dr. Maxim Freydin, Specialty Chief Editors of the Human and Medical Genomics section in Frontiers in Genetics, this Research Topic aims to illuminate the strides made over the past decade within the realm of human and medical genomics field, providing a comprehensive overview of past achievements while dissecting future challenges. The primary focus is to showcase progress and pinpoint the existing hurdles that still need to be surmounted to push the boundaries of what's medically and technically feasible in genetics.

To gather further insights within this rapidly developing field, we welcome articles addressing, but not limited to, the following themes:
• Novel genomic technologies and their clinical application
• Genetic determinants of complex diseases
• Ethical, legal, and social implications of genomic research
• Personalized medicine and genomic tailoring
• Advances in genomic sequencing techniques
• Integration of genomic data with AI and machine learning approaches

These contributions should reflect the state-of-the-art, detail recent developments, and highlight pivotal accomplishments, emphasizing on advancing knowledge and applications within the field.

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Frontiers in Genetics

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