The escalating problem of antibiotic resistance poses a critical threat to global health, diminishing the effectiveness of traditional therapies against various pathogens. Emerging infectious diseases further exacerbate this challenge, requiring innovative treatment strategies. Advanced drug delivery systems, such as nanoparticles and liposomes, offer targeted and controlled release of therapeutic agents, enhancing
efficacy and reducing side effects. Concurrently, natural compounds, known for their potent antimicrobial properties, present a promising alternative or adjunct to conventional antibiotics. Integrating these cutting-edge technologies with natural compounds holds significant potential to develop effective, sustainable treatments for combating antibiotic resistance and emerging infectious diseases.
This Research Topic aims to tackle the pressing issue of antibiotic resistance and the treatment of emerging infectious diseases by exploring the potential of combining advanced drug delivery systems with natural compounds and extracts. Antibiotic resistance is a worldwide concern, rendering traditional therapies increasingly ineffective against various pathogens. For this, the development of innovative approaches to enhance therapeutic efficacy and reduce resistance is needed.
Recent advances in nanotechnology have led to the development of new drug delivery systems, such as
nanoparticles, liposomes, and hydrogels, which can provide targeted, controlled, and sustained release of therapeutic agents. Concurrently, natural compounds have demonstrated potent antimicrobial properties and unique mechanisms of action, offering a promising adjunct or alternative to conventional antibiotics.
By integrating these cutting-edge drug delivery technologies with natural compounds, we aim to enhance the effectiveness of treatments, minimize side effects, and reduce the development of resistance. This Research Topic will investigate the synergistic effects, develop targeted therapies, evaluate their efficacy and safety, and foster interdisciplinary collaboration to drive innovation and translate research findings into practical applications. Through these efforts, we hope to contribute to the development of effective, sustainable solutions for combating antibiotic resistance and emerging infectious diseases
This topic will focus on innovative drug delivery systems, including but not limited to the use of natural compounds and compounds, and their potential application in treating emerging infectious diseases. The aim is to explore how new drug delivery technologies and natural compounds can improve therapeutic efficacy, reduce side effects, and overcome antibiotic resistance. We welcome original articles, reviews, and brief research reports addressing one or various of the following:
• Design, synthesis, and characterization of drug delivery systems (nanoparticles,
liposomes, hydrogels, and other materials) combined with natural compounds.
• Synergistic effects of natural compounds in combination with conventional antibiotics in drug delivery systems.
• Strategies for the targeted delivery of natural compounds or extracts to specific tissues or pathogens.
• Evaluation of the pharmacokinetics and pharmacodynamics of these integrated systems.
• Investigations into how these novel therapies can prevent or overcome antibiotic resistance.
• Comparative effectiveness of these innovative therapies versus traditional treatments.
• Toxicity of these systems and limitations for their therapeutic application in infectious diseases.
• Mechanisms of action of natural compounds against various pathogens, including bacteria, viruses, fungi, and parasites.
• Physicochemical interactions of natural compounds with drug delivery systems’s matrix.
• Challenges in regulatory approval for new therapies and strategies for translating research findings into clinical practice
Keywords:
Drug delivery systems, Natural extracts, Natural compounds, Antibiotic Resistance, Emerging infectious Disease, Controlled realese, Targeted therapy, Combination therapy
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
The escalating problem of antibiotic resistance poses a critical threat to global health, diminishing the effectiveness of traditional therapies against various pathogens. Emerging infectious diseases further exacerbate this challenge, requiring innovative treatment strategies. Advanced drug delivery systems, such as nanoparticles and liposomes, offer targeted and controlled release of therapeutic agents, enhancing
efficacy and reducing side effects. Concurrently, natural compounds, known for their potent antimicrobial properties, present a promising alternative or adjunct to conventional antibiotics. Integrating these cutting-edge technologies with natural compounds holds significant potential to develop effective, sustainable treatments for combating antibiotic resistance and emerging infectious diseases.
This Research Topic aims to tackle the pressing issue of antibiotic resistance and the treatment of emerging infectious diseases by exploring the potential of combining advanced drug delivery systems with natural compounds and extracts. Antibiotic resistance is a worldwide concern, rendering traditional therapies increasingly ineffective against various pathogens. For this, the development of innovative approaches to enhance therapeutic efficacy and reduce resistance is needed.
Recent advances in nanotechnology have led to the development of new drug delivery systems, such as
nanoparticles, liposomes, and hydrogels, which can provide targeted, controlled, and sustained release of therapeutic agents. Concurrently, natural compounds have demonstrated potent antimicrobial properties and unique mechanisms of action, offering a promising adjunct or alternative to conventional antibiotics.
By integrating these cutting-edge drug delivery technologies with natural compounds, we aim to enhance the effectiveness of treatments, minimize side effects, and reduce the development of resistance. This Research Topic will investigate the synergistic effects, develop targeted therapies, evaluate their efficacy and safety, and foster interdisciplinary collaboration to drive innovation and translate research findings into practical applications. Through these efforts, we hope to contribute to the development of effective, sustainable solutions for combating antibiotic resistance and emerging infectious diseases
This topic will focus on innovative drug delivery systems, including but not limited to the use of natural compounds and compounds, and their potential application in treating emerging infectious diseases. The aim is to explore how new drug delivery technologies and natural compounds can improve therapeutic efficacy, reduce side effects, and overcome antibiotic resistance. We welcome original articles, reviews, and brief research reports addressing one or various of the following:
• Design, synthesis, and characterization of drug delivery systems (nanoparticles,
liposomes, hydrogels, and other materials) combined with natural compounds.
• Synergistic effects of natural compounds in combination with conventional antibiotics in drug delivery systems.
• Strategies for the targeted delivery of natural compounds or extracts to specific tissues or pathogens.
• Evaluation of the pharmacokinetics and pharmacodynamics of these integrated systems.
• Investigations into how these novel therapies can prevent or overcome antibiotic resistance.
• Comparative effectiveness of these innovative therapies versus traditional treatments.
• Toxicity of these systems and limitations for their therapeutic application in infectious diseases.
• Mechanisms of action of natural compounds against various pathogens, including bacteria, viruses, fungi, and parasites.
• Physicochemical interactions of natural compounds with drug delivery systems’s matrix.
• Challenges in regulatory approval for new therapies and strategies for translating research findings into clinical practice
Keywords:
Drug delivery systems, Natural extracts, Natural compounds, Antibiotic Resistance, Emerging infectious Disease, Controlled realese, Targeted therapy, Combination therapy
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.