The reproductive system is fundamental to life, influencing health and well-being through the creation of new life and hormonal regulation. Given the complex interplay of environmental, lifestyle, and genetic factors that influence fertility, comprehensive research into the genomic mechanisms regulating male and female fertility is critical. Such studies not only advance medical science but also provide crucial insights for developing and implementing public health policies.

This research topic aims to collect original research, review articles, and clinical case reports focused on the genomic regulation of fertility in both men and women. By bringing together cutting-edge studies, we seek to facilitate academic exchange, foster collaboration among researchers, and drive advancements in fertility research. Our goal is to provide novel insights and methodologies that can enhance clinical treatments and ultimately support individuals and couples striving for reproductive success.

We invite experts and scholars from various disciplines to contribute original research, comprehensive reviews, and clinical case reports on the genomic regulation of male and female fertility. Your contributions will help drive scholarly exchanges, spark innovative ideas and methodologies, and significantly advance both academic and clinical practices in reproductive medicine. Potential topics include but are not limited to the following:

• Investigating intricate genetic pathways governing sperm capacitation and male infertility, uncovering critical molecular mechanisms involved in fertilization and sperm motility, including protein post-translational modifications that act as regulatory processes in male fertility.

• Evaluating pharmacological interventions for male infertility, with a focus on promising drug treatments assessed in animal and cellular models, and examining the genetic basis of drug response.

• Exploring the biological mechanisms underlying female fertility regulation, with an emphasis on premature ovarian failure and age-related ovarian function decline. Investigating pharmacological treatment strategies targeting female ovarian aging, assessing their impact on reproductive outcomes, and integrating genomic data to personalize treatment approaches.

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Frontiers in Genetics

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