The realm of immunotherapies is at the forefront of medical advancements, particularly in the fields of drug delivery and tissue regeneration. Fueled by the imperative to address a wide swath of immunological ailments ranging from chronic deficiencies to cancers, these therapies employ sophisticated methods to modulate the immune system effectively. Crucially, recent studies have highlighted novel strategies, such as immune reprogramming, delivering promising results in improving treatment efficacy while minimizing adverse effects. Despite these leaps, challenges persist over pinpointing optimal delivery methods and mitigating potential side effects, indicating substantial room for groundbreaking research and development.

This Research Topic aims to showcase the cutting-edge breakthroughs and innovative applications of immunotherapies in drug delivery and tissue regeneration. By exploring various therapies, including vaccines, checkpoint inhibitors, and CAR-T cell strategies, the research seeks to unravel their mechanisms and enhance therapeutic precision and safety, grounding an uncharted territory in treatment modalities.

To gather further insights across the broad applications of immunotherapies in drug delivery and tissue regeneration, we welcome articles addressing, but not limited to, the following themes:

- Targeted Drug and Cell Delivery for enhanced therapeutic precision
- Immune Checkpoint Inhibitors for advanced or combined Immunotherapy
- Chimeric Antigen Receptor CAR T-Cell therapy
- Vaccine Development for Cancer and Infectious Diseases
- Immune Modulation for Healing: wound healing, macrophage polarization in tissue repair, cytokine therapy for regulating inflammation responses
- Stem Cell Therapy: engineering cells for modulating immune responses and implant rejection, creating regenerative niches for biomimetic properties
- Biomaterials and Immunomodulatory Scaffolds for promoting tissue regeneration
- Gene Editing of immune or stem cells for enhanced genetic and regenerative capabilities

This comprehensive focus enables a rich exploration of both theoretical advancements and practical applications, offering a vital contribution to the evolving science of immunotherapies.

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Frontiers in Biomaterials Science

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