About this Research Topic
Translational research and innovative therapies have opened new frontiers in understanding atopic dermatitis (AD), focusing on key areas such as abnormal immune responses, pruritus, microbial imbalances, and skin barrier defects. The application of advanced genomic technologies and targeted therapies has unveiled intricate details of the disease's molecular basis, exposing how factors like the IL-13, OX40-axis, and Staphylococcus aureus contribute to its pathogenesis. This knowledge has led to a reevaluation of the itch-scratch cycle and its impact on skin integrity, highlighting the interplay between various biochemical pathways.
This Research Topic aims to deepen our understanding of AD by addressing the complexities introduced by patient heterogeneity and the evolving landscape of therapeutic strategies. By exploring targeted treatments, small molecule applications, and the overarching role of microorganisms and biomarkers in therapeutics, this research seeks to refine clinical approaches and enhance patient-specific outcomes.
To gather further insights in the diverse manifestations and treatments of AD, we welcome articles addressing, but not limited to, the following themes:
• Molecular and cellular mechanisms related to immune abnormalities, pruritus, dysbiosis, and barrier defects.
• Emerging insights in the neuroimmunology of AD.
• Cutting-edge therapeutic mechanisms in AD management.
• Advanced omic studies elucidating the multifaceted pathogenesis of AD.
• The development and application of biomarkers in AD diagnosis and therapy.
Translational research and innovative therapies have opened new frontiers in understanding atopic dermatitis (AD), focusing on key areas such as abnormal immune responses, pruritus, microbial imbalances, and skin barrier defects. The application of advanced genomic technologies and targeted therapies has unveiled intricate details of the disease's molecular basis, exposing how factors like the IL-13, OX40-axis, and Staphylococcus aureus contribute to its pathogenesis. This knowledge has led to a reevaluation of the itch-scratch cycle and its impact on skin integrity, highlighting the interplay between various biochemical pathways.
This Research Topic aims to deepen our understanding of AD by addressing the complexities introduced by patient heterogeneity and the evolving landscape of therapeutic strategies. By exploring targeted treatments, small molecule applications, and the overarching role of microorganisms and biomarkers in therapeutics, this research seeks to refine clinical approaches and enhance patient-specific outcomes.
To gather further insights in the diverse manifestations and treatments of AD, we welcome articles addressing, but not limited to, the following themes:
• Molecular and cellular mechanisms related to immune abnormalities, pruritus, dysbiosis, and barrier defects.
• Emerging insights in the neuroimmunology of AD.
• Cutting-edge therapeutic mechanisms in AD management.
• Advanced omic studies elucidating the multifaceted pathogenesis of AD.
• The development and application of biomarkers in AD diagnosis and therapy
This Research Topic aims to deepen our understanding of AD by addressing the complexities introduced by patient heterogeneity and the evolving landscape of therapeutic strategies. By exploring targeted treatments, small molecule applications, and the overarching role of microorganisms and biomarkers in therapeutics, this research seeks to refine clinical approaches and enhance patient-specific outcomes.
To gather further insights in the diverse manifestations and treatments of AD, we welcome articles addressing, but not limited to, the following themes:
• Molecular and cellular mechanisms related to immune abnormalities, pruritus, dysbiosis, and barrier defects.
• Emerging insights in the neuroimmunology of AD.
• Cutting-edge therapeutic mechanisms in AD management.
• Advanced omic studies elucidating the multifaceted pathogenesis of AD.
• The development and application of biomarkers in AD diagnosis and therapy.
Translational research and innovative therapies have opened new frontiers in understanding atopic dermatitis (AD), focusing on key areas such as abnormal immune responses, pruritus, microbial imbalances, and skin barrier defects. The application of advanced genomic technologies and targeted therapies has unveiled intricate details of the disease's molecular basis, exposing how factors like the IL-13, OX40-axis, and Staphylococcus aureus contribute to its pathogenesis. This knowledge has led to a reevaluation of the itch-scratch cycle and its impact on skin integrity, highlighting the interplay between various biochemical pathways.
This Research Topic aims to deepen our understanding of AD by addressing the complexities introduced by patient heterogeneity and the evolving landscape of therapeutic strategies. By exploring targeted treatments, small molecule applications, and the overarching role of microorganisms and biomarkers in therapeutics, this research seeks to refine clinical approaches and enhance patient-specific outcomes.
To gather further insights in the diverse manifestations and treatments of AD, we welcome articles addressing, but not limited to, the following themes:
• Molecular and cellular mechanisms related to immune abnormalities, pruritus, dysbiosis, and barrier defects.
• Emerging insights in the neuroimmunology of AD.
• Cutting-edge therapeutic mechanisms in AD management.
• Advanced omic studies elucidating the multifaceted pathogenesis of AD.
• The development and application of biomarkers in AD diagnosis and therapy
Keywords: atopic dermatitis, immunology, neuroimmunology, translational research, skin dysbiosis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
