About this Research Topic
Given the dynamic nature of this field, our objective is to delve deeper into the developments and perspectives of the most talked-about articles of the year. We are keen to explore how these significant contributions have shaped and will continue to influence the trajectory of research in this domain. By fostering a vibrant dialogue, we hope to uncover new insights and future directions in epigenetic research.
The featured manuscripts include:
• Epigenetic clocks derived from western samples differentially reflect Taiwanese health outcomes.
• Investigating the impact of metformin on the epigenetic age of peripheral blood in diabetes mellitus patients.
• Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer.
• Conducting a transcriptome-wide analysis of RNA N6-Methyladenosine modification in Adriamycin-resistant acute myeloid leukemia cells.
• Unveiling the molecular mediators linking child obesity and mental health.
• Examining the effects of fear stress during pregnancy on placental m6A-modifying enzyme expression and epigenetic modification levels.
• Rare diseases of epigenetic origin: Challenges and opportunities.
• Understanding the mechanisms that govern DNA damage protein accessibility to constitutive heterochromatin.
• Deciphering the influence of 3D genome organization on breast cancer susceptibility.
We envision this Research Topic as a platform for researchers to share their unique perspectives and contribute to a broad and nuanced understanding of these key articles. This initiative not only celebrates latest advancements made, but also sets the stage for emerging research and collaborative opportunities in the year ahead.
We welcome submissions in the form of Opinions, Perspectives, Hypotheses and Theory, and Mini Review articles that contribute meaningfully to the discourse on these selected papers. Each submission will be carefully evaluated to ensure that it adds a significant contribution to the ongoing discussion and sparks further investigation.
Join us in this intellectual endeavour to highlight and critique the milestone research works that continue to push the boundaries of Epigenomics and Epigenetics. Together, we can pave the way for future innovations and discoveries.
Keywords: metformin, diabetes, DNA damage protein, heterochromatin, molecular mediators, child obesity, mental health, N6-Methyladenosine, Leukemia, 3D genome, breast cancer, fear, stress, pregnancy, placental, m6A
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.