Bioprinting is a rapidly developing technique to fabricate complex and biomimetic structures for tissue engineering and regenerative medicine applications. The technology has evolved from simplistic mono-material structures to complex multi-material and functional tissue constructs. The development of novel biomaterials has enabled new bio-ink formulations that broaden the printability window and provide cell-instructive properties. Strategies such as embedding bioprinting, electro-writing, microfluidic printing, and tomographic volumetric printing are furthering the complexity of structures that can be fabricated. This convergence of technologies, strategies, and materials is facilitating the next generation of tissue engineering applications and disease models that are beginning to find real-world use.

The goal of this Research Topic is to highlight the latest advancements in technologies, strategies, and materials that are enabling the translation of bioprinting into clinically viable therapies and models. This can be through addressing key challenges in the field of tissue engineering such as the development of vascularised thick constructs, cell-instructive bio-inks/bio-resins/hydrogels, and biological functionality. Alternatively, new and improved technologies are increasing the capability of bioprinting to fabricate high-resolution multi-material and complex structures. Finally, novel strategies that can overcome limitations in bioprinting or provide enhanced models.

This research topic aims to collect the latest advances in the field of bioprinting including state-of-the-art comprehensive reviews, focused mini-reviews, and novel original research articles. The scope includes but are not limited to topics such as:

- bioink/bioresin/hydrogel design and development

- tissue-specific studies (in vitro and in vivo)

- disease models, and bioprinting technologies.

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Frontiers in Biomaterials Science

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