About this Research Topic
Stem cells play a crucial role in treating various diseases by their ability to regenerate damaged tissues and differentiate into specialized cells. They are used to repair heart tissue after heart attacks, restore damaged kidney cells, and generate dopamine-producing neurons for Parkinson's disease. These cells are also integral to cell therapy, where they are directly injected into damaged tissues to stimulate repair and regeneration. This approach has shown promise in treating conditions like osteoarthritis and spinal cord injuries. Furthermore, induced pluripotent stem cells (iPSCs), which are adult cells reprogrammed to a pluripotent state, offer a promising avenue for generating patient-specific cells that can avoid immune rejection issues.
Stem Cells are used in tissue engineering to create lab-grown tissues for transplantation, providing new treatment options for conditions such as severe burns and cardiac diseases. The potential to regenerate entire organs, such as kidneys or hearts, is being actively researched, which could address the critical shortage of organ donors. Additionally, stem cells facilitate disease modeling and drug discovery by allowing researchers to study disease progression and test new drugs in a controlled environment. Their versatility and regenerative capabilities make them a cornerstone of innovative therapies, offering hope for conditions previously deemed incurable and improving patients' quality of life.
This Research Topic aims to provide a comprehensive, contemporary collection of research focusing on exploring stem cell engineering. We welcome Original Research Articles, Reviews, Mini-Reviews, Systematic Reviews, Perspectives, Commentaries, Data notes, and technical notes, but are not limited to the following:
• Tissue Engineering: Innovating methods to engineer complex tissues and organs for transplantation and regenerative medicine.
• Disease Modeling: Using stem cells to create in vitro disease models, facilitating the study of disease mechanisms and the screening of new treatments.
• Biomaterials and Scaffolds: Designing biomimetic materials and scaffolds that support stem cell growth, differentiation, and tissue regeneration in engineered structures.
• Gene Editing and Manipulation: Applying genetic engineering techniques to enhance stem cells' therapeutic potential and achieve targeted modifications.
Keywords: Stem Cell. Induced Pluripotent Stem Cells (iPSCs), Pluripotent, Regenerative Medicine, Cell Proliferation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.