This Research Topic is the second volume of 'Case Reports in Cardiovascular Genetics and Systems Medicine'. Please see the first volume here: https://www.frontiersin.org/research-topics/33174

This Research Topic aims to collect all the Case Reports submitted to the 'Cardiovascular Genetics and Systems Medicine' section. If submitted directly to this collection the paper will be personally assessed by the Specialty Chief Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.

Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course:
1) Rare cases with Typical features
2) Frequent cases with Atypical features
3) Cases with a convincing response to new treatments, i.e. single case of off-label use

Case Report format:
- Maximum word count: 3000 words
- Title: Case Report: “area of focus”
- Abstract.
- Introduction: including what is unique about the case and medical literature references.
- Case description: including de-identified patient information, relevant physical examination and other clinical findings, relevant past interventions, and their outcomes.
- A figure or table showcasing a timeline with relevant data from the episode of care.
- Diagnostic assessment, details on the therapeutic intervention, follow-up, and outcomes, as specified in the CARE guidelines.
- Discussion: strengths and limitations of the approach to the case, discussion of the relevant medical literature (similar and contrasting cases), take-away lessons from the case.
- Patient perspective.

Please, note that authors are required to obtain written informed consent from the patients (or their legal representatives) for the publication.

IMPORTANT: Only Case Reports that are original and significantly advance the field will be considered.

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Frontiers in Cardiovascular Medicine

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