With recent advancements in computational methods, researchers now have unprecedented access to vast amounts of data generated from various sources, such as high-throughput sequencing, mass spectrometry, and advanced imaging technologies. This wealth of data provides both opportunities and challenges in unravelling the complexities of the immune system in ways previously unimaginable.

Artificial intelligence (AI) has emerged as a powerful tool in immunology, facilitating the identification of patterns and correlations within complex biological data. This shows the potential application to the discovery of novel biomarkers, predict disease progression, and even suggest personalized treatment strategies. Moreover, AI-driven approaches can enhance the reproducibility and accuracy of immunological research. Deep learning models can analyze imaging data with high precision, while natural language processing can streamline the review of vast scientific literature, ensuring that researchers remain up-to-date with the latest advancements.

As the volume and complexity of immunological data continue to grow, by harnessing the power of AI, researchers can accelerate the pace of discovery and deepen our understanding of immune system dynamics and pathologies, ultimately leading to more effective diagnostics and therapeutics.

This research topic seeks to foster an interdisciplinary approach to immunological research, encouraging collaborative efforts between computational and life scientists. This is crucial for both the development of new analytical methods and the experimental validation of findings.

This special issue aims to collect Original Research, Review, Mini Review, and Perspective articles focused on the application of artificial intelligence methods to enhance our understanding of the immune system and immune-mediated disorders. Topics of interest include, but are not limited to, novel computational methods (including machine learning) tailored for immunological research, diagnosis and management of immune-mediated disorders, curated datasets and data-driven investigations of immune dynamics.

Studies whose main finding were not obtained employing computational methods, and studies that describe computational methods without direct application for immunological research are not within the scope of this section.

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Frontiers in Immunology

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