Human Immunodeficiency Virus (HIV) infection remains a significant global health challenge, affecting millions of individuals worldwide. While antiretroviral therapy (ART) has transformed HIV into a manageable chronic condition, patients still face numerous complications, including oxidative stress-induced damage. Oxidative stress plays a crucial role in HIV pathogenesis, contributing to disease progression, immune dysfunction, and the development of comorbidities. Addressing oxidative stress in HIV represents a critical area of research to enhance patient outcomes and quality of life.
This Research Topic aims to explore the intricate relationship between oxidative stress and HIV infection while highlighting innovative strategies for mitigating oxidative damage in affected individuals. By bringing together leading researchers, clinicians, and experts in the field, we seek to:
• Investigate the molecular mechanisms underlying oxidative stress in HIV infection.
• Explore the impact of oxidative stress on HIV pathogenesis, disease progression, and comorbidity development.
• Review current diagnostic methods for assessing oxidative stress markers in HIV-infected individuals.
• Showcase novel therapeutic interventions and mitigation strategies targeting oxidative stress in HIV.
• Discuss the role of lifestyle modifications, nutrition, and adjunctive therapies in reducing oxidative burden and improving patient outcomes.
• Examine the interaction between oxidative stress and ART, including potential oxidative side effects and ways to counteract them.
• Identify biomarkers of oxidative stress that could be used for early detection and monitoring of HIV progression.
• Evaluate the genetic and epigenetic factors influencing oxidative stress responses in HIV-infected individuals.
• Investigate the role of oxidative stress in HIV-associated neurocognitive disorders.
• Explore the potential of antioxidant therapies in improving the efficacy of ART and reducing drug resistance.
We welcome original research articles, reviews, perspectives, and addressing the role of oxidative stress in HIV/AIDS. Manuscripts should adhere to the journal's formatting and submission guidelines. Authors are encouraged to provide novel insights, rigorous methodology, and potential clinical implications in their submissions. Contributions from multidisciplinary perspectives are particularly valued to foster comprehensive discussions and advancements in this critical area of research.
Keywords:
oxidative stress, HIV Pathogenesis, Antioxidant Therapy, Disease Progression, Comorbidities
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Human Immunodeficiency Virus (HIV) infection remains a significant global health challenge, affecting millions of individuals worldwide. While antiretroviral therapy (ART) has transformed HIV into a manageable chronic condition, patients still face numerous complications, including oxidative stress-induced damage. Oxidative stress plays a crucial role in HIV pathogenesis, contributing to disease progression, immune dysfunction, and the development of comorbidities. Addressing oxidative stress in HIV represents a critical area of research to enhance patient outcomes and quality of life.
This Research Topic aims to explore the intricate relationship between oxidative stress and HIV infection while highlighting innovative strategies for mitigating oxidative damage in affected individuals. By bringing together leading researchers, clinicians, and experts in the field, we seek to:
• Investigate the molecular mechanisms underlying oxidative stress in HIV infection.
• Explore the impact of oxidative stress on HIV pathogenesis, disease progression, and comorbidity development.
• Review current diagnostic methods for assessing oxidative stress markers in HIV-infected individuals.
• Showcase novel therapeutic interventions and mitigation strategies targeting oxidative stress in HIV.
• Discuss the role of lifestyle modifications, nutrition, and adjunctive therapies in reducing oxidative burden and improving patient outcomes.
• Examine the interaction between oxidative stress and ART, including potential oxidative side effects and ways to counteract them.
• Identify biomarkers of oxidative stress that could be used for early detection and monitoring of HIV progression.
• Evaluate the genetic and epigenetic factors influencing oxidative stress responses in HIV-infected individuals.
• Investigate the role of oxidative stress in HIV-associated neurocognitive disorders.
• Explore the potential of antioxidant therapies in improving the efficacy of ART and reducing drug resistance.
We welcome original research articles, reviews, perspectives, and addressing the role of oxidative stress in HIV/AIDS. Manuscripts should adhere to the journal's formatting and submission guidelines. Authors are encouraged to provide novel insights, rigorous methodology, and potential clinical implications in their submissions. Contributions from multidisciplinary perspectives are particularly valued to foster comprehensive discussions and advancements in this critical area of research.
Keywords:
oxidative stress, HIV Pathogenesis, Antioxidant Therapy, Disease Progression, Comorbidities
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.