About this Research Topic
The regenerative microenvironment is a crucial factor in governing tissue regeneration. Previous research has indicated that inflammation within this environment can be detrimental to tissue healing. However, recent studies increasingly propose that inflammation comprises multiple effectors and effector cells, each assuming distinct roles at various stages of tissue injury and regeneration. For instance, M1 macrophages are responsible for eliminating exogenous microorganisms and damaged cells during the early stages of injury, followed by a gradual increase in M2 macrophages that contribute to tissue repair. Furthermore, complete suppression of inflammation at an early stage may not be conducive to tissue regeneration. These findings highlight the limited extent of our current understanding of inflammation in tissue regeneration, warranting further exploration. Advancing our comprehension of inflammation has the potential to facilitate the development of novel drugs and technologies aimed at promoting tissue repair and regeneration in the future.
Inflammation represents a pivotal component of the regenerative microenvironment, and precise regulation of inflammatory factors and cells is crucial for ensuring the speed and quality of tissue regeneration. Several cytokines have been clinically approved for use in wound repair, instilling confidence in the industrialization of related products. Urgent issues that require understanding include, but are not limited to, key factors contributing to alterations in inflammatory homeostasis, the functional subtypes of inflammatory cells and their methods of identification, the effects of inflammatory factors and cells on stem cells, the impacts of cellular and related therapeutic technologies on tissue regeneration, and the impact of novel bioengineered materials on the regenerative microenvironment. It is anticipated that this topic will help us discover key factors governing inflammation and regeneration, and delve into the intrinsic link between inflammation and regeneration, thereby propelling the advancement of associated therapeutic technologies.
The role of inflammation in tissue regeneration
Key mechanisms regulating the dynamics of inflammation
Role of inflammatory effectors and inflammatory cells in tissue regeneration
The effects of inflammation on stem cell niches
Effects of stem cell therapy and its derivatives on inflammation
Impact of immune disorders on tissue regeneration
Impact of novel tissue engineering materials on the regenerative inflammatory microenvironment
Key regulatory factors governing stem cell proliferation, differentiation, transdifferentiation, and dedifferentiation
The effect of immunotherapy on tissue regeneration
Inflammation represents a pivotal component of the regenerative microenvironment, and precise regulation of inflammatory factors and cells is crucial for ensuring the speed and quality of tissue regeneration. Several cytokines have been clinically approved for use in wound repair, instilling confidence in the industrialization of related products. Urgent issues that require understanding include, but are not limited to, key factors contributing to alterations in inflammatory homeostasis, the functional subtypes of inflammatory cells and their methods of identification, the effects of inflammatory factors and cells on stem cells, the impacts of cellular and related therapeutic technologies on tissue regeneration, and the impact of novel bioengineered materials on the regenerative microenvironment. It is anticipated that this topic will help us discover key factors governing inflammation and regeneration, and delve into the intrinsic link between inflammation and regeneration, thereby propelling the advancement of associated therapeutic technologies.
The role of inflammation in tissue regeneration
Key mechanisms regulating the dynamics of inflammation
Role of inflammatory effectors and inflammatory cells in tissue regeneration
The effects of inflammation on stem cell niches
Effects of stem cell therapy and its derivatives on inflammation
Impact of immune disorders on tissue regeneration
Impact of novel tissue engineering materials on the regenerative inflammatory microenvironment
Key regulatory factors governing stem cell proliferation, differentiation, transdifferentiation, and dedifferentiation
The effect of immunotherapy on tissue regeneration
Keywords: : inflammation, regeneration, tissue repair, wound healing, stem cells
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