Marine life is an underexplored reservoir for providing sustainable nutrients and diverse diets. The special environment of the ocean determines the structural characteristics of marine active substances. Marine-derived sulfated polysaccharides consist of branched chains and sulfated groups, such as glycosaminoglycans (heparin, chondroitin sulfate, etc.) in marine animals and carrageenan, ulvan, etc. in marine plants. These sulfated polysaccharides show many bioactivities, such as anti-inflammatory, anti-obesity, and antiviral properties, etc. Sulfated polysaccharides have been developed for use in the amelioration of chronic diseases, such as obesity, diabetes and colitis. Improving evidence has proven that the structure of sulfated polysaccharides is highly associated with its bioactivities, such as molecular weight, sulfated degree, etc. Subtle differences in structure lead to large differences in biological activity. Therefore, the development of extraction and modification methods for sulfated polysaccharides has attracted increased interest. Elucidation of the conformational mechanisms of polysaccharides is an important requirement for the development of precision nutrition strategies.
This research topic aims to deepen our understanding of the effect of sulfated polysaccharides on human health, such as preventing chronic diseases, improving malnutrition, etc. Furthermore, this research topic aims to elucidate the effects of sulfated polysaccharides in precision nutrition and reveal the underlying structure-function relationship. The collection of more efficient methods for extracting and modifying sulfated polysaccharides is important to advance the field. In addition, exploring the molecular mechanism of the bioactivity of sulfated polysaccharides based on their structural features for the development of precision nutrition.
We welcome submissions of Original Research, Systematic Review, Mini Review, and Perspectives that focus on but not limited to the following topics:
• Effects of sulfated polysaccharides and their influence on host health through alleviating clinical symptoms, regulating inflammation or modulating gut microbiota composition.
• Identifying key factors (key microbes, specific metabolites, etc.) regulated by sulfated polysaccharide and their relationship to host health.
• Collection of research results on extraction and modification methods of sulfated polysaccharides, such as new extraction methods, modification techniques to regulate molecular weight, etc.
• Development of novel nutrition strategies based on the effect of sulfated polysaccharides (such as chondroitin sulfate, carrageen, ulvan, etc.) on precision nutrition.
• Systematic exploration of mechanisms and molecular foundations of sulfated polysaccharides in the prevention or treatment of chronic disease (such as colitis, obesity, type 2 diabetes mellitus, etc.) during the dietary intervention.
Keywords:
Sulfated polysaccharides, Marine food, Nutrition, Gut microbiota, Metabolites
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Marine life is an underexplored reservoir for providing sustainable nutrients and diverse diets. The special environment of the ocean determines the structural characteristics of marine active substances. Marine-derived sulfated polysaccharides consist of branched chains and sulfated groups, such as glycosaminoglycans (heparin, chondroitin sulfate, etc.) in marine animals and carrageenan, ulvan, etc. in marine plants. These sulfated polysaccharides show many bioactivities, such as anti-inflammatory, anti-obesity, and antiviral properties, etc. Sulfated polysaccharides have been developed for use in the amelioration of chronic diseases, such as obesity, diabetes and colitis. Improving evidence has proven that the structure of sulfated polysaccharides is highly associated with its bioactivities, such as molecular weight, sulfated degree, etc. Subtle differences in structure lead to large differences in biological activity. Therefore, the development of extraction and modification methods for sulfated polysaccharides has attracted increased interest. Elucidation of the conformational mechanisms of polysaccharides is an important requirement for the development of precision nutrition strategies.
This research topic aims to deepen our understanding of the effect of sulfated polysaccharides on human health, such as preventing chronic diseases, improving malnutrition, etc. Furthermore, this research topic aims to elucidate the effects of sulfated polysaccharides in precision nutrition and reveal the underlying structure-function relationship. The collection of more efficient methods for extracting and modifying sulfated polysaccharides is important to advance the field. In addition, exploring the molecular mechanism of the bioactivity of sulfated polysaccharides based on their structural features for the development of precision nutrition.
We welcome submissions of Original Research, Systematic Review, Mini Review, and Perspectives that focus on but not limited to the following topics:
• Effects of sulfated polysaccharides and their influence on host health through alleviating clinical symptoms, regulating inflammation or modulating gut microbiota composition.
• Identifying key factors (key microbes, specific metabolites, etc.) regulated by sulfated polysaccharide and their relationship to host health.
• Collection of research results on extraction and modification methods of sulfated polysaccharides, such as new extraction methods, modification techniques to regulate molecular weight, etc.
• Development of novel nutrition strategies based on the effect of sulfated polysaccharides (such as chondroitin sulfate, carrageen, ulvan, etc.) on precision nutrition.
• Systematic exploration of mechanisms and molecular foundations of sulfated polysaccharides in the prevention or treatment of chronic disease (such as colitis, obesity, type 2 diabetes mellitus, etc.) during the dietary intervention.
Keywords:
Sulfated polysaccharides, Marine food, Nutrition, Gut microbiota, Metabolites
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.