The immune system, a complex network comprising cells, tissues, and organs, defends the body against pathogens and diseases. However, disruptions in immune homeostasis, especially the overactivated lymphocytes can lead to autoimmune diseases such as rheumatoid arthritis and lupus. A thorough understanding of the mechanisms of cell development and the precise interaction among lymphocytes is crucial for the effective prevention and treatment of autoimmune diseases. Detailed measurement and monitoring of the lymphocytes are essential for advancing research in this field, potentially leading to breakthroughs in therapeutic strategies and improved understanding of disease pathology—thereby enhancing patient outcomes and quality of life.

This Research Topic aims to cover the latest developments in the measurement parameters, monitoring indicators, cellular or molecular mechanisms, clinical outcomes, and advanced therapeutic strategies concerning lymphocytes and Autoimmune Diseases. We particularly highlight the mechanisms related to common autoimmune disorders such as lupus and rheumatoid arthritis, focusing on the most pressing unanswered questions and providing guidelines for future research in this dynamic area, including other facets of autoimmunity.

We encourage the submission of manuscripts that explore, but are not limited to, the following areas:

1. Biomarkers and diagnostic approaches for autoimmune diseases.
2. Innovative treatment strategies for autoimmune diseases.
3. Cellular and molecular mechanisms underpinning autoimmune diseases.
4. B cell and T cell aberrations in autoimmune diseases.
5. Cell development and precise interactions among immune cells in autoimmune diseases.
6. Broader health aspects related to autoimmune diseases.

Through this Research Topic, we aim to open a new window into possible multidisciplinary strategies for understanding and managing autoimmune diseases. We welcome diverse manuscript types that contribute to this growing field of research.

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Frontiers in Immunology

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