About this Research Topic
The interplay between diet, obesity, and cancer has garnered significant attention over the past three decades, as adult obesity rates have more than doubled and adolescent rates have quadrupled. Currently, 2.5 billion adults are classified as overweight, with 890 million living with obesity. This condition is a multifaceted health concern linked to various diseases, including heart disease, diabetes, high blood pressure, and notably, certain types of cancers. The obesogenic environment and unhealthy eating behaviors are key drivers of this epidemic, with high intake of saturated and trans fats contributing to weight gain and abdominal obesity. Despite ongoing research, the precise mechanisms by which obesity influences cancer risk remain incompletely understood. Recent studies have highlighted the role of metabolic disorders, hormonal imbalances, and gut microbiota dysbiosis in mediating this risk, yet gaps in knowledge persist, necessitating further investigation.
This Research Topic aims to elucidate the complex relationships between diet, obesity, and cancer. Specifically, it seeks to answer questions regarding how dietary factors contribute to obesity and how obesity, in turn, influences cancer risk and progression. The Research Topic will test hypotheses related to the mechanisms of obesity-mediated cancer development, including the roles of inflammation, hormonal imbalances, and gut microbiota. By addressing these questions, the collection aims to advance therapeutic strategies and improve patient outcomes.
To gather further insights into the intricate connections between diet, obesity, and cancer, we welcome articles addressing, but not limited to, the following themes:
• Nutrigenomics and personalized approaches to cancer prevention in obesity.
• Effect of diet and obesity on the tumor microenvironment.
• Role of diet and gut microbiota in mediating the obesity-cancer link.
• Role of diet and obesity-associated hormonal imbalance in cancer risk and progression.
• Influence of diet on epigenetic modifications in obesity-related cancer.
This Research Topic aims to elucidate the complex relationships between diet, obesity, and cancer. Specifically, it seeks to answer questions regarding how dietary factors contribute to obesity and how obesity, in turn, influences cancer risk and progression. The Research Topic will test hypotheses related to the mechanisms of obesity-mediated cancer development, including the roles of inflammation, hormonal imbalances, and gut microbiota. By addressing these questions, the collection aims to advance therapeutic strategies and improve patient outcomes.
To gather further insights into the intricate connections between diet, obesity, and cancer, we welcome articles addressing, but not limited to, the following themes:
• Nutrigenomics and personalized approaches to cancer prevention in obesity.
• Effect of diet and obesity on the tumor microenvironment.
• Role of diet and gut microbiota in mediating the obesity-cancer link.
• Role of diet and obesity-associated hormonal imbalance in cancer risk and progression.
• Influence of diet on epigenetic modifications in obesity-related cancer.
Keywords: Cancer, Obesity, Metabolism, Personalized Nutrition, Nutrigenomic, Epigenetic Modifications, Tumor Microenvironment, Cancer Risk, Cancer Progression
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
