Virology has experienced transformative shifts with the advent of biosensors and CRISPR/Cas systems, reshaping how viral infections are diagnosed. Biosensors excel in rapidly and sensitively detecting viral pathogens, providing real-time data, portability, and superior sensitivity. Concurrently, the CRISPR/Cas systems, initially lauded for their gene-editing prowess, have demonstrated their utility in identifying viral nucleic acids with unprecedented precision. Through programmable detection of DNA and RNA sequences, these systems promise to deliver high-accuracy diagnostic tools. Together, biosensors and CRISPR/Cas systems synergize to potentially revolutionize virology by enhancing the diagnostic accuracy, speed, and accessibility of detecting viral infections.

This Research Topic aims to highlight and advance the integration of biosensor and CRISPR/Cas systems in virology. It seeks to explore novel techniques and applications that enhance the diagnosis and monitoring of viral ailments, testing the limits and capabilities of these technologies in current and novel scenarios.

Focusing on the interaction between biosensor technologies and CRISPR/Cas systems within the realm of virology, this topic invites studies across a broad spectrum. To foster innovation and collaboration in developing state-of-the-art diagnostic platforms, contributions may include, but are not limited to, the following themes:

o Discovery of new Cas enzymes
o Innovative biosensor designs
o Real-time monitoring of viral load using biosensors
o Integrated biosensor and CRISPR/Cas systems for rapid diagnosis of viral infections
o Application of these technologies in virological research settings
o Amplification-free detection methods
o Ultrasensitive and one-pot detection techniques
o Simplification of molecular diagnostic tests
o Bioengineered biosensors for improved diagnostic accuracy
o Collaborative approaches in CRISPR-based diagnostics
o Novel systems and methods enhancing viral diagnostics
o Broad applications in diagnosing viruses in various health contexts such as pandemics, chronic infections, and veterinary medicine.

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Frontiers in Virology

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