About this Research Topic
In this research topic, we aim to address the critical need for better biomarkers that can predict therapeutic outcomes and guide immunotherapy decisions. Contributors are encouraged to present studies that contribute to a holistic view of the tumor immune environment, focusing on the discovery and validation of biomarkers that can predict response to treatment and aid in the development of more effective immunotherapeutic strategies.
This Research Topic accepts Original Research papers, Reviews, Mini-Reviews, Perspectives, Case Reports, and Brief Research Reports. We welcome manuscripts focusing on, but not limited to, the following sub-topics:
1. Advanced multi-omics techniques for profiling immunological landscapes in head and neck cancers.
2. Integration of genomic, proteomic, and metabolomic data to uncover novel immunotherapeutic targets and biomarkers.
3. Case studies and clinical trials that utilize multi-omics data to tailor immunotherapeutic approaches.
4. Cross-disciplinary analyses that bridge immunological research with clinical applications, focusing on the translational aspect of scientific discoveries.
5. Research that explores the underlying pathophysiological mechanisms of HNC through the lens of multi-omics and immunology.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Keywords: head and neck Cancer, immunology, multi-omics, immunotherapeutic biomarkers, tumor microenvironment, translational research
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.