Epigenetic regulation plays a pivotal role in the pathogenesis of fibrosis, a pathological condition characterized by excessive deposition of extracellular matrix components, leading to tissue scarring and dysfunction of various organs including heart, liver, lung, kidney, skin etc. Understanding the intricate interplay between epigenetic mechanisms, such as DNA methylation, histone modifications, and non-coding RNA regulation, and the activation of fibrogenic pathways holds great promise for novel therapeutic target identification and precision medicine development for related disease treatment. This research topic aims to explore the dynamic epigenetic changes underlying fibrosis, understand the molecular mechanisms driving disease progression, and identify potential therapeutic interventions to mitigate fibrosis.
The primary goal of this research topic is to address the gap in our understanding of epignetic mechanisms involved in fibrosis. We aim to bring together researchers to explore how epigenetic changes influence the initiation and progression of fibrotic diseases. Furthermore, this research topic will also highlight potential therapeutic interventions and precision medicine approaches that can be utilized to mitigate fibrosis by targeting various epigenetic pathways. We hope this research topic can finally facilitate the clinical treatment of patients with fibrotic diseases.
This research topic invites contributions that cover a broad range of themes related to epigenetic regulation in fibrosis. We are particularly interested in studies focusing on: Mechanisms and functions of DNA, histone, or other chromatin modification in fibrosis; Non-coding RNA regulation and function in fibrosis; Mechanisms and functions of RNA modification and function in fibrosis; epigenetic regulation related fibrosis mitigation and treatment. We welcome original research articles, reviews, and perspectives that provide new insights into the epigenetic landscape of fibrosis. Authors from diverse affiliations and geographic regions are encouraged to contribute, ensuring a comprehensive and global perspective on this critical area of research.
Keywords:
fibrosis, DNA methylation, Epigenetics, Histone Modification, RNA modification, Non-coding RNA, Fibrogenesis pathways, Extracellular Matrix, Precision medicine development
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Epigenetic regulation plays a pivotal role in the pathogenesis of fibrosis, a pathological condition characterized by excessive deposition of extracellular matrix components, leading to tissue scarring and dysfunction of various organs including heart, liver, lung, kidney, skin etc. Understanding the intricate interplay between epigenetic mechanisms, such as DNA methylation, histone modifications, and non-coding RNA regulation, and the activation of fibrogenic pathways holds great promise for novel therapeutic target identification and precision medicine development for related disease treatment. This research topic aims to explore the dynamic epigenetic changes underlying fibrosis, understand the molecular mechanisms driving disease progression, and identify potential therapeutic interventions to mitigate fibrosis.
The primary goal of this research topic is to address the gap in our understanding of epignetic mechanisms involved in fibrosis. We aim to bring together researchers to explore how epigenetic changes influence the initiation and progression of fibrotic diseases. Furthermore, this research topic will also highlight potential therapeutic interventions and precision medicine approaches that can be utilized to mitigate fibrosis by targeting various epigenetic pathways. We hope this research topic can finally facilitate the clinical treatment of patients with fibrotic diseases.
This research topic invites contributions that cover a broad range of themes related to epigenetic regulation in fibrosis. We are particularly interested in studies focusing on: Mechanisms and functions of DNA, histone, or other chromatin modification in fibrosis; Non-coding RNA regulation and function in fibrosis; Mechanisms and functions of RNA modification and function in fibrosis; epigenetic regulation related fibrosis mitigation and treatment. We welcome original research articles, reviews, and perspectives that provide new insights into the epigenetic landscape of fibrosis. Authors from diverse affiliations and geographic regions are encouraged to contribute, ensuring a comprehensive and global perspective on this critical area of research.
Keywords:
fibrosis, DNA methylation, Epigenetics, Histone Modification, RNA modification, Non-coding RNA, Fibrogenesis pathways, Extracellular Matrix, Precision medicine development
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.