Imaging techniques in nanomedicine must enable the visualization of the nano-constructs inside the cells or tissue, ensuring optimal preservation of the structural features and the spatial relationships of nanoparticles with the tissue components, while preserving, in the case of in vivo studies, the viability and physiological function of the organism. The possibility to track nanomedicine has a plethora of goals, especially the intent to better understand the role of these systems in the efficacy and safety before a potential human use. Moreover, the theranostic is a valid strategy to track drugs loaded into nanocarrier and make early diagnosis and treatment of the disease. Currently, researchers have explored different strategies to track nanomedicine, such as loading or stably binding the fluorescent dye and/or radioactive to the nanostructure, or stimuli responsive. Each strategy showed advantages and/or disadvantages and it is strictly combined with the type of equipment used for the investigation.

This Research Topic will focus on the investigation of nanomedicine for imaging scope to obtain relevant information about the fate or interaction of the nanocarriers at biological levels (in vivo biodistribution or in vitro interactions) including subcellular systems. The main goal of this Research Topic is to explore the application of nanomedicine in preclinical investigations, both for diagnostic and theranostic goals, in healthy tissue or in disease models that affect different tissues or organs. The investigation should include deep characterization of nanocarriers and biological evaluations.

We welcome Original Research Articles and Review Articles that deeply explore the physicochemical, technological, and morphological properties of innovative nanocarriers. Mandatory are biological studies on in vitro cells or in vivo on healthy animals or in animal disease models.

The collection will focus on themes that include, but are not limited to:
- Nanomedicine and In vitro imaging;
- Nanomedicine and In vivo imaging;
- Nanomedicine and brain diseases;
- Applications in the life science and medical fields.

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Frontiers in Drug Delivery

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