Biomaterials and biologicals are pivotal in disease treatment, enabling precise drug delivery and enhanced efficacy while minimizing side effects. Biomaterial-based systems utilize biocompatible carriers for controlled drug release, optimizing therapeutic outcomes. Moreover, incorporating biological components enhances specificity, utilizing ligand-receptor interactions for targeted delivery. These innovations revolutionize disease management, offering tailored treatments across diverse medical domains, from cancer therapies to regenerative medicine. With ongoing advancements, these smart delivery systems promise to redefine precision therapeutics, ushering in a new era of personalized and effective treatments.

The objective of this research topic is to investigate recent advancements, design principles, and challenges in utilizing biomaterials and biologicals for disease treatment. Through the publication of full papers, short articles, reviews, and opinions, we aim to comprehensively address aspects of design, synthesis, characterization, and evaluation of these innovative treatment modalities. Key areas of focus include biomaterial-drug interactions, precision drug release mechanisms, and in vivo efficacy evaluations. By promoting the application of biomaterials and biologicals in clinical therapeutics, we aim to offer novel insights and methodologies for advancing disease treatment strategies.

The main scope of the research topic includes but is not limited to
1. Design, preparation and characterization of biological agents;
2. Mechanisms and factors influencing drug-biomaterial interactions;
3. Biomaterials with controlled release;
4. In vivo effectiveness assessment and application of biological agents;
5. Development and application of novel drug delivery technologies and methods;
6. Design of smart drug release carriers/hydrogel dressings;
7. Biological agents or biomaterials for drug, cellular and exosomal delivery;
8. Current status and prospects of biologics development ;
9. Drug delivery systems for phage therapy.

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Frontiers in Bioengineering and Biotechnology

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