Biosensors and bioelectronics play an important role in our daily lives. Biosensors can be generally categorized into physical sensors, which measure physical quantities such as mechanical, thermal and hydraulic values that can be used for various biomedical applications such as measuring blood pressure and body temperature, or chemical sensors, which detect chemical quantities such as analyte concentrations to monitor body activities, aiding diagnostic processes.

Biomaterials open the doors for in vivo sensing, allowing for real time in-body sensing, with minimal or no negative impact on patients. Technologies such as additive manufacturing have been increasingly used in producing customisable and complex structures. In particular, additive manufacturing allows for the accurate translation of CAD models directly into working models. 3D printing is a great candidate for sensor production as it offers rapid production, customisation, and ability to produce complex structures. Biosensors, chemical and physical sensors all can be produced using 3D printing utilizing either direct complete printing, component printing, producing moulds for sensors casting, or producing integrated circuitry and panels.

This Research Topic aims to provide details on the use of biomaterials and additive manufacturing of micro and nano sensors, as well as the challenges and future aspects of biosensing. Sensors are devices that can detect an input and use it to produce an output: there are various principles to consider when designing sensors, such as sensing element (biological or non biological sensing element), working principle (i.e. electrochemical, optical, etc…), sensor architecture and operation framework. The main focus of progress in sensor design are the rapid production, customisation, miniaturisation and complexity. While there has been substantial progression in terms of sensing materials and approaches, there are still crucial challenges for fully producing a completely additively manufactured sensor, using biomaterials and sensing systems, which will be explored in this Topic.

We welcome the submission of Original Research, Review, Mini Review, and Perspective articles on themes including, but not limited to:

• The role of Additive manufacturing processes in the fabrication of (bio-) sensors

• Various applications of additive manufactured (bio-) sensors in biomedical applications.

• Incorporation of biomaterials in (bio-) sensors

• Different types of additive manufacturing techniques for fabrication of biomedical-based (bio-) sensors.

• Additive manufacturing of electronics, sensors and biosensors for diseases detection

• Sensor design theory/ approach

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Frontiers in Biomaterials Science

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