Retinal ischemia, often referred to as the “stroke of the retina,” plays a significant role in visual impairment associated with conditions such as diabetic retinopathy, retinopathy of prematurity, retinal vascular occlusion, and acute glaucoma. Recent evidence highlights the involvement of oxidative stress and inflammatory processes in the pathogenesis of ischemic retinopathies (IRs). In the ischemic retina, excessive production of free radicals leads to neurodegeneration, inflammation, glial cell activation, and vascular damage.
While current therapies, including photocoagulation and anti-VEGF treatment, offer benefits, there remains a critical need to identify novel therapeutic targets for these ocular pathologies. A deeper understanding of the molecular mechanisms underlying various IRs can pave the way for the development of innovative treatment approaches. This Research Topic aims to showcase recent advances in our knowledge of IRs, emphasizing promising biomolecules and therapeutic strategies.
We welcome original research, comprehensive reviews, and methodological articles that shed light on different aspects of ischemic retinopathies. Together, we can unlock new avenues for effective interventions and improved visual outcomes.
Keywords:
ischemic retinopathies, diabetic retinopathy, retinopathy of prematurity, retinal vascular occlusion, acute glaucoma, photocoagulation, anti-VEGF
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Retinal ischemia, often referred to as the “stroke of the retina,” plays a significant role in visual impairment associated with conditions such as diabetic retinopathy, retinopathy of prematurity, retinal vascular occlusion, and acute glaucoma. Recent evidence highlights the involvement of oxidative stress and inflammatory processes in the pathogenesis of ischemic retinopathies (IRs). In the ischemic retina, excessive production of free radicals leads to neurodegeneration, inflammation, glial cell activation, and vascular damage.
While current therapies, including photocoagulation and anti-VEGF treatment, offer benefits, there remains a critical need to identify novel therapeutic targets for these ocular pathologies. A deeper understanding of the molecular mechanisms underlying various IRs can pave the way for the development of innovative treatment approaches. This Research Topic aims to showcase recent advances in our knowledge of IRs, emphasizing promising biomolecules and therapeutic strategies.
We welcome original research, comprehensive reviews, and methodological articles that shed light on different aspects of ischemic retinopathies. Together, we can unlock new avenues for effective interventions and improved visual outcomes.
Keywords:
ischemic retinopathies, diabetic retinopathy, retinopathy of prematurity, retinal vascular occlusion, acute glaucoma, photocoagulation, anti-VEGF
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.