The therapeutic potential of adult multipotent and pluripotent stem cells has garnered significant attention in recent years. These cells, found in various tissues, possess the ability to differentiate into a wide range of specialized cell types, offering great promise for regenerative medicine and tissue repair. Despite their distinct advantages, unlocking their full potential presents challenges, including the need for precise differentiation, ethical concerns, and the risk of tumorigenicity. Recent studies have demonstrated promising results in the use of these stem cells for treating various conditions, including neurodegenerative diseases, cardiovascular disorders, and tissue injuries. However, significant gaps remain in our understanding of the molecular mechanisms governing stem cell behaviour, as well as in the development of reliable and safe differentiation protocols. Addressing these challenges is crucial for advancing the field and translating scientific discoveries into clinical applications.

This research topic aims to comprehensively explore the therapeutic implications, advancements, and challenges associated with adult multipotent and pluripotent stem cells. By synthesizing current knowledge and recent breakthroughs, it seeks to elucidate the potential of these cells in regenerative medicine applications, such as tissue repair and disease treatment. Furthermore, the research addresses critical issues like the development of precise differentiation protocols, safety concerns, and ethical considerations surrounding the use of adult stem cells. Ultimately, this inquiry aims to enhance the understanding of adult stem cell biology and facilitate the translation of scientific discoveries into clinical therapies, thereby fostering the advancement of regenerative medicine approaches for diverse medical conditions.

To gather further insights into the therapeutic potential of adult multipotent and pluripotent stem cells, we welcome articles addressing, but not limited to, the following themes:
- Molecular mechanisms underlying stem cell differentiation
- Innovative technologies for the isolation and characterization of stem cells
- Applications of stem cells in specific disease models
- Safety and ethical considerations in stem cell research
- Challenges in translating stem cell research into clinical applications.

We invite original research articles and reviews that contribute to a deeper understanding of adult stem cell biology and its practical implications in regenerative medicine. Authors are encouraged to present cutting-edge research, critically assess current methodologies, and propose future directions in the field.

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Frontiers in Molecular Biosciences

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