Immunoregulation and treatment of allergic diseases

The occurrence of allergic diseases has been increased in recent years worldwide. However, there is no known cure for those diseases, and treatments usually involves several restrictions to contact with antigens and use of immunosuppressive drugs that can compromise patient’s health. Knowing that, it is necessary to understand the molecular and immunological mechanisms involved in allergy to develop effective treatments that are minimally harmful to health.

This Research Topic aims to investigate the current understanding of molecular and immunological mechanisms involved in various allergic responses, depending on the location (such as gut, skin, lungs) or type of allergen (such as egg, milk protein, seafood, peanuts). Furthermore, the characterization of the mechanisms involved in allergies will enrich knowledge and facilitate the development of new approaches less harmful regarding allergic diseases. Suitable themes include but are not limited to:

• Identification and characterization of new pathways relevant to allergic response.
• Tissue-specific response to allergens.
• Allergic responses during viral or bacterial infections.
• Molecular blocking of axis related to allergic response.
• Immunotherapies and vaccines to antigens.
• Comparison between allergic responses to different allergens.
• Immunoregulation related to abrogation of allergies.
• Discover of new drugs used as treatment of allergy.
• Modulation of microbiota in allergy.

Keywords: immunoregulation, food allergy, allergic diseases, cell response, oral tolerance

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.