About this Research Topic
Cancer remains a significant challenge in medical research and treatment, prompting the exploration of innovative strategies for more effective therapeutic interventions. Among these approaches, immunotherapy has emerged as a promising avenue by harnessing the body's immune system to identify and eliminate cancer cells. In recent years, there has been increasing interest in utilizing immunomodulatory molecules derived from natural sources as novel tools in the fight against cancer.
Natural products have historically served as a rich source of pharmacologically active compounds, many of which exhibit immunomodulatory properties. These molecules can interact with various components of the immune system, bolstering its capacity to recognize and eradicate cancer cells while minimizing harm to healthy tissues. By capitalizing on the immunomodulatory characteristics of natural compounds, researchers are exploring fresh avenues for cancer therapy that not only target the tumor cells directly but also engage the host immune system. These approaches show promise for enhancing treatment outcomes, mitigating adverse effects, and overcoming resistance to conventional therapies. However, further research is imperative to fully understand the mechanisms of action underlying natural immunomodulators, optimize dosing protocols, and evaluate their safety and efficacy in clinical settings. Ultimately, the integration of natural products into cancer treatment strategies represents a compelling approach to advancing precision medicine and personalized oncology. In this context, let's explore some of the key immunomodulatory molecules sourced from natural origins and their potential as innovative strategies for tackling cancer.
The sub-topics to be covered within the issue should be provided:
- Traditional Medicinal Plants in Cancer Immunotherapy
- Targeting Tumor Microenvironment in Immunomodulation: Role of Plant Compounds
- Multi-level immune regulation mechanisms related to various cancers
- Plant-Derived Immunomodulators against Cancer: Exploring Nature's Arsenal
- Bioavailability of immunomodulatory cancer drugs
- Clinical perspective of natural immunomodulation in cancer
- Gut microbiota regulation and Immune modulation in cancer
- Challenges and Opportunities: Integrating Plant-Based Therapies in Oncology
Valid compounds of natural origin in the Pharmacology of Anti-Cancer Drugs section refer to biologically active substances from natural sources like plants, marine organisms, and microorganisms. These compounds, such as vinca alkaloids, taxanes, trabectedin, and anthracyclines, demonstrate anti-cancer properties by altering the life cycle of cancer cells or the tumour microenvironment. These compounds are validated through extensive, scientifically rigorous research demonstrating their effectiveness and safety in treating cancer.
In addition, for manuscripts dealing with plant extracts or other natural substances/compounds, the composition and the stability of the study material must be described in sufficient detail. In particular, for extracts, chromatograms with characterization of the dominating compound(s) are requested. The level of purity must be proven and included.
Please note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent clinical or patient cohort, or biological validation in vitro or in vivo, which are not based on public databases) are not suitable for publication in this journal.
Natural products have historically served as a rich source of pharmacologically active compounds, many of which exhibit immunomodulatory properties. These molecules can interact with various components of the immune system, bolstering its capacity to recognize and eradicate cancer cells while minimizing harm to healthy tissues. By capitalizing on the immunomodulatory characteristics of natural compounds, researchers are exploring fresh avenues for cancer therapy that not only target the tumor cells directly but also engage the host immune system. These approaches show promise for enhancing treatment outcomes, mitigating adverse effects, and overcoming resistance to conventional therapies. However, further research is imperative to fully understand the mechanisms of action underlying natural immunomodulators, optimize dosing protocols, and evaluate their safety and efficacy in clinical settings. Ultimately, the integration of natural products into cancer treatment strategies represents a compelling approach to advancing precision medicine and personalized oncology. In this context, let's explore some of the key immunomodulatory molecules sourced from natural origins and their potential as innovative strategies for tackling cancer.
The sub-topics to be covered within the issue should be provided:
- Traditional Medicinal Plants in Cancer Immunotherapy
- Targeting Tumor Microenvironment in Immunomodulation: Role of Plant Compounds
- Multi-level immune regulation mechanisms related to various cancers
- Plant-Derived Immunomodulators against Cancer: Exploring Nature's Arsenal
- Bioavailability of immunomodulatory cancer drugs
- Clinical perspective of natural immunomodulation in cancer
- Gut microbiota regulation and Immune modulation in cancer
- Challenges and Opportunities: Integrating Plant-Based Therapies in Oncology
Valid compounds of natural origin in the Pharmacology of Anti-Cancer Drugs section refer to biologically active substances from natural sources like plants, marine organisms, and microorganisms. These compounds, such as vinca alkaloids, taxanes, trabectedin, and anthracyclines, demonstrate anti-cancer properties by altering the life cycle of cancer cells or the tumour microenvironment. These compounds are validated through extensive, scientifically rigorous research demonstrating their effectiveness and safety in treating cancer.
In addition, for manuscripts dealing with plant extracts or other natural substances/compounds, the composition and the stability of the study material must be described in sufficient detail. In particular, for extracts, chromatograms with characterization of the dominating compound(s) are requested. The level of purity must be proven and included.
Please note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent clinical or patient cohort, or biological validation in vitro or in vivo, which are not based on public databases) are not suitable for publication in this journal.
Keywords: Immunomodulatory, Cancer, Tumor, Targeting, Natural
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