About this Research Topic
This research topic aims to explore the discovery of immune modulators and drugs that can directly influence the immune response to enhance recovery after cardiac injury and mitigate adverse remodeling. The primary objective is to identify and test potential therapeutic interventions that target specific immune cells, such as M2-like macrophages, natural killer cells, regulatory T cells, and engineered immune cells like CAR-T cells. Additionally, the research will consider the potential of modifying the immune system to address issues related to aging and failing hearts, with a focus on reducing fibrosis and senescence.
To gather further insights in the realm of immune modulation for cardiovascular health, we welcome articles addressing, but not limited to, the following themes:
- The role of specific immune cells in cardiac repair and remodeling.
- Novel drug discoveries targeting immune pathways in heart disease.
- Mechanisms of immune cell-mediated cardiac protection and repair.
- The impact of immune modulation on aging and fibrotic cardiac tissues.
- Advances in engineered immune cells for therapeutic applications in cardiology.
- Clinical trials and case studies on immunotherapeutic strategies for heart disease.
Manuscripts dealing with complementary medicine or traditional medicine do not fit the scope of this journal.
Topic Editor Dr. Ioakim Spyridopoulos received financial support from Astra Zeneca and Kancera.. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Keywords: Inflammation, Immune cells, Cardiovascular diseases, T-cells, Novel drug discovery, immunotherapeutic strategies, Macrophages
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.