About this Research Topic
In recent years, the field of nanobiosensors has witnessed significant advancements, playing a pivotal role in healthcare, environmental monitoring, and food safety. These sensors combine nanomaterials with biological elements such as cells, enzymes, and antibodies, enabling the detection and quantification of target analytes at the nanoscale. Diverse nanomaterials, ranging from DNA to quantum dots and carbon nanotubes to graphene, metal nanoparticles, and polymers, have been employed in their construction. Further, their functionalization with recognition elements amplifies specificity and selectivity. Besides, the rapid and sensitive detection of diverse pathogens has driven the utilization of nanobiosensors for antibiotic detection, marking a promising and emerging field of research. This advancement is crucial in addressing global challenges like antimicrobial resistance (AMR), nosocomial infections, and antibiotic contamination in food. By quickly identifying antibiotic residues and resistant strains, nanobiosensors will enable targeted interventions to control the spread of drug-resistant pathogens.
Widespread AMR resulting from overuse and misuse in medical and agricultural contexts has led to a global antibiotic crisis, and AMR is predicted to become a leading cause of death in the coming decades. The situation has caused common antibiotics to be less effective, leading to prolonged illnesses, heightened healthcare costs, and increased mortality rates. Meanwhile, the slow pace of antibiotic development worsens the situation, with few new drugs entering the market. Additionally, nosocomial infections caused by antibiotic-resistant pathogens contribute to elevated morbidity and mortality. Meanwhile, agricultural misuse contributes to antibiotic residues in food, posing environmental and human health risks. Hence, the crisis necessitates innovative strategies, like the use of nanobiosensors, to address the growing threat of AMR and ensure the continued effectiveness of antibiotics in treating bacterial infections. Although various detection techniques, including chromatography, immunoassays, and microbiological assays, have been employed to address the challenges, the methods are often time-consuming, expensive, labor-intensive, may lack sensitivity or selectivity, exhibit cross-reactivity, and require large-scale equipment. While nanobiosensors offer a promising solution for the rapid and accurate determination of antibiotic resistance at the nanoscale.
This research topic explores cutting-edge nanobiosensors developed for the detection of antibiotics. Addressing the need to combat global problems posed by antibiotic resistance, the focus is on nanomaterial-driven and DNA-based sensor development. Contributors are urged to explore advanced functionalization techniques that enhance specificity and selectivity. Beyond healthcare, the applications of nanosensors in environmental settings, particularly for detecting antibiotic contamination, and in ensuring food safety through the identification of antibiotic residues, should be examined.
We welcome original research, comprehensive reviews, and methodological papers that demonstrate technological innovations, specific applications, and the contributions of nanobiosensors in addressing the complexities surrounding antibiotic resistance and misuse, promoting interdisciplinary collaborations across nanotechnology, biology, and medicine.
Widespread AMR resulting from overuse and misuse in medical and agricultural contexts has led to a global antibiotic crisis, and AMR is predicted to become a leading cause of death in the coming decades. The situation has caused common antibiotics to be less effective, leading to prolonged illnesses, heightened healthcare costs, and increased mortality rates. Meanwhile, the slow pace of antibiotic development worsens the situation, with few new drugs entering the market. Additionally, nosocomial infections caused by antibiotic-resistant pathogens contribute to elevated morbidity and mortality. Meanwhile, agricultural misuse contributes to antibiotic residues in food, posing environmental and human health risks. Hence, the crisis necessitates innovative strategies, like the use of nanobiosensors, to address the growing threat of AMR and ensure the continued effectiveness of antibiotics in treating bacterial infections. Although various detection techniques, including chromatography, immunoassays, and microbiological assays, have been employed to address the challenges, the methods are often time-consuming, expensive, labor-intensive, may lack sensitivity or selectivity, exhibit cross-reactivity, and require large-scale equipment. While nanobiosensors offer a promising solution for the rapid and accurate determination of antibiotic resistance at the nanoscale.
This research topic explores cutting-edge nanobiosensors developed for the detection of antibiotics. Addressing the need to combat global problems posed by antibiotic resistance, the focus is on nanomaterial-driven and DNA-based sensor development. Contributors are urged to explore advanced functionalization techniques that enhance specificity and selectivity. Beyond healthcare, the applications of nanosensors in environmental settings, particularly for detecting antibiotic contamination, and in ensuring food safety through the identification of antibiotic residues, should be examined.
We welcome original research, comprehensive reviews, and methodological papers that demonstrate technological innovations, specific applications, and the contributions of nanobiosensors in addressing the complexities surrounding antibiotic resistance and misuse, promoting interdisciplinary collaborations across nanotechnology, biology, and medicine.
Keywords: Nanobiosensor, Antimicrobial resistance, Antibiotic detection, nanomaterial, recognition element, DNA-based sensor
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
