Biopolymer composites, which combine biodegradable polymers with natural materials, have gained significant attention for their potential in controlled drug delivery systems. This research topic focuses on the development, characterization, and application of biopolymer composite materials as drug delivery platforms to facilitate regenerative pharmacology.

This research topic explores the synergy between biopolymer composite materials and regenerative pharmacology, focusing on the development of innovative drug delivery systems that can enhance the regenerative potential of pharmacological agents while addressing biocompatibility and sustainability concerns. It offers an interdisciplinary approach with relevance to both the fields of materials science and pharmacology.

We would like to include articles in the form of Original Research, Review/Opinion/Perspective, and Clinical Trial/Case Report. We invite contributions that relate to, but are not limited to, the following topics:

• Biopolymer Composite Formulations: Investigate the design and formulation of biopolymer composites, combining biodegradable polymers with natural materials such as chitosan, alginate, cellulose, or hyaluronic acid. Explore various fabrication techniques and their impact on drug release profiles.

• Drug Loading and Release: Examine the loading capacities and controlled release properties of biopolymer composites for regenerative pharmacology. How can drug release kinetics be tailored to support tissue regeneration and repair?

• Biocompatibility and Cytotoxicity: Evaluate the biocompatibility and cytotoxicity of biopolymer composite drug delivery systems. Investigate their suitability for delivering pharmacological agents to regenerating tissues without adverse effects.

• Targeted Drug Delivery: Explore strategies for targeted drug delivery using biopolymer composites, such as surface modifications, nanoparticles, or microspheres. How can these systems be optimized for specific regenerative applications?

• Regenerative Pharmacology Applications: Investigate the use of biopolymer composites for delivering regenerative pharmacological agents, including growth factors, stem cell therapies, and small molecules, in various tissue regeneration contexts, such as bone, cartilage, nerve, or skin.

• Scaffold Integration: Discuss the integration of biopolymer composite drug delivery systems with tissue engineering scaffolds. How can these composites provide mechanical support while delivering regenerative drugs to the target site?

• In Vivo Studies: Present in vivo studies and animal models assessing the efficacy of biopolymer composite drug delivery systems in promoting tissue regeneration. Evaluate their performance, safety, and long-term effects.

• Clinical Translatability: Address the translational potential of biopolymer composite drug delivery platforms for clinical regenerative medicine. What are the regulatory challenges, and how can these systems be brought to the bedside?

• Sustainability and Environmental Impact: Discuss the sustainability and environmental implications of biopolymer composites, considering their biodegradability and eco-friendliness.

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Frontiers in Pharmacology

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