About this Research Topic
The emergence and global spread of viral-induced infectious diseases have long been a challenge to public health. Throughout history, these diseases have posed significant threats, with pandemics like COVID-19 serving as stark reminders of the devastating impact such viruses can have on a global scale. The ongoing evolution of viral strains, coupled with factors like increased globalization and urbanization, makes it imperative to develop effective antiviral agents to safeguard public health and global health security.
Recent advances in computational biology and biotechnology have opened up new avenues for identifying and developing antiviral agents. In-silico drug design, which combines computational methods and molecular modeling, offers a rapid and cost-effective means to screen and design potential antiviral compounds. Additionally, experimental techniques allow for the validation of in-silico predictions, ensuring that identified candidates are both effective and safe. Despite these advancements, there remains a critical need for more comprehensive studies that integrate both computational and experimental approaches to address the gaps in our current understanding and development of antiviral agents.
This research topic aims to converge cutting-edge computational and experimental techniques to battle viral infectious diseases by identifying and refining antiviral agents. By targeting viral-induced infectious ailments, this initiative aims to make substantial strides towards fortifying global health security. Specifically, the research seeks to employ advanced computational tools and methodologies to screen and design potential antiviral compounds, conduct comprehensive experimental validation of promising antiviral candidates, enhance our knowledge of selected compounds' antiviral mechanisms, and generate new insights that can inform the development of effective treatments for life-threatening viral infections.
To gather further insights in the realm of antiviral drug discovery and development, we welcome articles addressing, but not limited to, the following themes:
- In-Silico Drug Designing: Identify potential antiviral agents targeting specific viral proteins.
- Quantitative Structure-Activity Relationship (QSAR)/Pharmacophore Modeling: Predict the activity of antiviral candidates and optimize their chemical structures.
- Drug Repurposing: Explore existing drugs for their potential antiviral effects against different viral infections, with a focus on rapid identification and testing of candidates.
- Natural Phytochemicals and Food Products: Study the potential of natural compounds and food products as immune boosters and antiviral agents against human-infecting viruses.
- Biophysical and In Vitro Evaluation: Experimentally evaluate identified candidates, including biophysical studies and in vitro assays, to assess their antiviral activity and mechanism of action.
- In Vivo Assessment: Conduct animal model studies to evaluate the efficacy and safety of potent antiviral candidates in minimizing viral load and disease progression.
- Exploring Hypothetical Proteins: Investigate unidentified (hypothetical) proteins associated with viral infectious diseases, focusing on their potential as novel drug targets.
Recent advances in computational biology and biotechnology have opened up new avenues for identifying and developing antiviral agents. In-silico drug design, which combines computational methods and molecular modeling, offers a rapid and cost-effective means to screen and design potential antiviral compounds. Additionally, experimental techniques allow for the validation of in-silico predictions, ensuring that identified candidates are both effective and safe. Despite these advancements, there remains a critical need for more comprehensive studies that integrate both computational and experimental approaches to address the gaps in our current understanding and development of antiviral agents.
This research topic aims to converge cutting-edge computational and experimental techniques to battle viral infectious diseases by identifying and refining antiviral agents. By targeting viral-induced infectious ailments, this initiative aims to make substantial strides towards fortifying global health security. Specifically, the research seeks to employ advanced computational tools and methodologies to screen and design potential antiviral compounds, conduct comprehensive experimental validation of promising antiviral candidates, enhance our knowledge of selected compounds' antiviral mechanisms, and generate new insights that can inform the development of effective treatments for life-threatening viral infections.
To gather further insights in the realm of antiviral drug discovery and development, we welcome articles addressing, but not limited to, the following themes:
- In-Silico Drug Designing: Identify potential antiviral agents targeting specific viral proteins.
- Quantitative Structure-Activity Relationship (QSAR)/Pharmacophore Modeling: Predict the activity of antiviral candidates and optimize their chemical structures.
- Drug Repurposing: Explore existing drugs for their potential antiviral effects against different viral infections, with a focus on rapid identification and testing of candidates.
- Natural Phytochemicals and Food Products: Study the potential of natural compounds and food products as immune boosters and antiviral agents against human-infecting viruses.
- Biophysical and In Vitro Evaluation: Experimentally evaluate identified candidates, including biophysical studies and in vitro assays, to assess their antiviral activity and mechanism of action.
- In Vivo Assessment: Conduct animal model studies to evaluate the efficacy and safety of potent antiviral candidates in minimizing viral load and disease progression.
- Exploring Hypothetical Proteins: Investigate unidentified (hypothetical) proteins associated with viral infectious diseases, focusing on their potential as novel drug targets.
Keywords: Infectious diseases, In-silico studies, In-vitro assays, In-vivo assays, Biochemical and biophysical characterization, Antiviral drugs development
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
