About this Research Topic
Treating critically ill patients poses significant resource challenges, particularly in vulnerable populations, such as those in developing countries, which comprise 85.54% of the world’s population, or in austere conditions such as the initial surge of the COVID-19 pandemic. Inflammation is directly or indirectly associated with critical illness and can persist even after the disease has improved. Although anti-inflammatory pharmaceutical agents are commonly used, they are not always readily available and may have side effects.
Currently, there is limited literature exploring the effects of light, sound, nutrition, and movement in critical care settings. Previous studies have hypothesized that interventions in these areas could potentially reduce inflammation, regulate circadian rhythm, mitigate the complications associated with critical illness, and enhance the effectiveness of primary treatments. Considering the escalating healthcare costs, resource limitations, and concerns about drug side effects, it is imperative to explore alternative methods that can lower costs, expedite recovery, and decrease iatrogenic complications.
This Research Topic welcomes the submission of commentaries, reviews, and original research (retrospective, prospective, or meta-analysis). Themes to consider include (but are not limited to):
- Direct effects of light, movement (passive or active), sound (via noise control, music, frequencies, or prayer), or non-genetically modified nutrition to inflammation in critically ill patients.
-The association of one of these non-pharmacologic interventions to conditions attributed to inflammation such as sleep quality, circadian rhythm, delirium, anxiety, pain, hemodynamics, microbiota, or complications of critical illness such as critical illness polyneuropathy or chronic respiratory failure.
-Identification of populations that are susceptible or resistant to these non-pharmacologic interventions, noting also any racial/ethnic or geographic disparities.
-The modulation of current treatment such as initiation or duration of medications or the effects on hospital outcomes such as length of hospital or ICU stay, ventilator days, mortality, and quality of life with the development of protocols using these interventions.
There should be a discussion on the uniqueness of the research, how it compares to the current standard, resource utilization, and how it can be applicable in austere conditions, and outline the benefits and limitations associated with the proposed interventions.
COI: Dr. Ronaldo Go was commissioned to be part of a research group for Hoffemann-LaRoche for a post-COVID-19 study.
Currently, there is limited literature exploring the effects of light, sound, nutrition, and movement in critical care settings. Previous studies have hypothesized that interventions in these areas could potentially reduce inflammation, regulate circadian rhythm, mitigate the complications associated with critical illness, and enhance the effectiveness of primary treatments. Considering the escalating healthcare costs, resource limitations, and concerns about drug side effects, it is imperative to explore alternative methods that can lower costs, expedite recovery, and decrease iatrogenic complications.
This Research Topic welcomes the submission of commentaries, reviews, and original research (retrospective, prospective, or meta-analysis). Themes to consider include (but are not limited to):
- Direct effects of light, movement (passive or active), sound (via noise control, music, frequencies, or prayer), or non-genetically modified nutrition to inflammation in critically ill patients.
-The association of one of these non-pharmacologic interventions to conditions attributed to inflammation such as sleep quality, circadian rhythm, delirium, anxiety, pain, hemodynamics, microbiota, or complications of critical illness such as critical illness polyneuropathy or chronic respiratory failure.
-Identification of populations that are susceptible or resistant to these non-pharmacologic interventions, noting also any racial/ethnic or geographic disparities.
-The modulation of current treatment such as initiation or duration of medications or the effects on hospital outcomes such as length of hospital or ICU stay, ventilator days, mortality, and quality of life with the development of protocols using these interventions.
There should be a discussion on the uniqueness of the research, how it compares to the current standard, resource utilization, and how it can be applicable in austere conditions, and outline the benefits and limitations associated with the proposed interventions.
COI: Dr. Ronaldo Go was commissioned to be part of a research group for Hoffemann-LaRoche for a post-COVID-19 study.
Keywords: Light, Sound, Critical Illness, Mobility, Inflammation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
