The sector of the spinal cord and spine is undeniably a crucial component of modern neurosurgery. With the constant advancement of minimally invasive surgeries and the wide dissemination of medical knowledge, interest in the field of spinal cord and spine is on the rise. Given that the clinical symptoms of spinal cord and spine diseases can primarily be categorized as sensory impairments, motor function obstacles, and the loss of sphincter function, these conditions can significantly affect patients’ daily life and quality of life, leaving an indelible impact on their psyche. Therefore, rapid progress in this research spectrum is vital in ensuring society’s unity and stability at both national and global levels.

The diseases related to the spinal cord and spine are diverse, with variants such as cervical and lumbar degenerative diseases, intraspinal occupancies, intraspinal infections, syringomyelia, spinal arachnoiditis, Chiari malformations, spinal cord injuries, and spinal cord cysts among others. Accordingly, this proposal primarily focuses on studies related to the pathogenesis of various kinds of spinal cord and spine diseases, as well as the therapeutic effects of different microscopic surgical interventions, their outcomes, systematic and data-driven analysis of survival prognosis, physical therapy and follow-up rehabilitation.

We look at the detailed reportage of rare clinical cases and their literature reviews, novel physical therapy, and the use of adjuvant radiochemotherapy in treating malignant tumors, injuries, inflammations, degenerative diseases and other associated spinal cord and spine diseases.

This proposal intends to cover a broad range of article types, encouraging the surgical procedures and interventions involved in the manuscript to possess qualities such as “minimally invasive”, “low recurrence rate”, “highly targeted”, “cutting-edge”, and “highly representative”.

Till now, research into spinal cord and spine disease mechanisms remain largely unproven and contentious. The treatment strategies for malignant tumors are relatively monotonous, and solutions for injury repair are still ineffective. The application of peripheral nerve transplantation to spinal cord treatment has not been effectively implemented.

Therefore, the scope for research in the spinal cord and spine field is significant, with great potential for breakthroughs, and there is enormous anticipation for effective translation between basic experimental research and clinical research.

Please note that the Section of Neuro-oncology and Neurosurgical Oncology, also part of Frontiers in Oncology, does not accept articles that are purely in silico/bioinformatics based without clinical validation in patients (rather than rely solely on publicly available databases) and/or functional validation in vitro or in vivo.

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