About this Research Topic
Background:
Enlarged perivascular spaces (EPVS) have emerged as a topic of significant interest in the field of neurology, as they have been associated with various neurologic diseases and disorders. These fluid-filled spaces surrounding blood vessels in the brain play a crucial role in maintaining brain health, but their alterations and evolution in the context of neurologic conditions are not yet fully understood. Exploring the dynamic evolution of EPVS in different neurologic diseases, including neurodegenerative disorders, cerebrovascular diseases, and neuroinflammatory conditions, may offer valuable insights into disease progression, pathophysiology, and potential diagnostic and therapeutic targets.
Goal:
The primary goal of this Research Topic is to investigate the evolutionary patterns and clinical implications of enlarged perivascular spaces in neurologic diseases. By addressing the complex relationship between EPVS and various neurologic conditions, we aim to understand how these spaces evolve over time, their contribution to disease mechanisms, and the potential impact on patient outcomes and prognosis. By identifying patterns of EPVS evolution, we can potentially develop strategies for early detection, intervention, and monitoring of these spaces as neurologic diseases progress. Additionally, investigating the role of EPVS in disease progression may reveal novel targets for therapeutic interventions and preventive measures.
Scope and Information for Authors:
This Research Topic welcomes contributions from researchers across disciplines, including neurology, neuroscience, radiology, pathology, and translational medicine. We invite original research articles, review articles, case studies, and experimental studies that focus on, but are not limited to, the following themes:
• Longitudinal studies investigating the evolution of enlarged perivascular spaces in neurologic diseases
• Molecular and cellular mechanisms underlying the progression and remodeling of EPVS
• Associations between EPVS evolution and neurodegenerative disorders, cerebrovascular diseases, or neuroinflammatory conditions
• Imaging techniques and biomarkers for assessing the evolutionary patterns of EPVS
• Predictive value of EPVS evolution in the diagnosis, prognosis, and monitoring of neurologic diseases
• Therapeutic implications and interventions targeting EPVS progression and related neurologic conditions
By compiling diverse research perspectives, this Research Topic aims to enhance our understanding of the evolution of enlarged perivascular spaces in neurologic diseases and its clinical significance. The exchange of knowledge and collaboration among experts will help elucidate the underlying mechanisms, inform clinical management strategies, and potentially contribute to the development of novel therapeutic interventions for patients affected by these conditions.
Enlarged perivascular spaces (EPVS) have emerged as a topic of significant interest in the field of neurology, as they have been associated with various neurologic diseases and disorders. These fluid-filled spaces surrounding blood vessels in the brain play a crucial role in maintaining brain health, but their alterations and evolution in the context of neurologic conditions are not yet fully understood. Exploring the dynamic evolution of EPVS in different neurologic diseases, including neurodegenerative disorders, cerebrovascular diseases, and neuroinflammatory conditions, may offer valuable insights into disease progression, pathophysiology, and potential diagnostic and therapeutic targets.
Goal:
The primary goal of this Research Topic is to investigate the evolutionary patterns and clinical implications of enlarged perivascular spaces in neurologic diseases. By addressing the complex relationship between EPVS and various neurologic conditions, we aim to understand how these spaces evolve over time, their contribution to disease mechanisms, and the potential impact on patient outcomes and prognosis. By identifying patterns of EPVS evolution, we can potentially develop strategies for early detection, intervention, and monitoring of these spaces as neurologic diseases progress. Additionally, investigating the role of EPVS in disease progression may reveal novel targets for therapeutic interventions and preventive measures.
Scope and Information for Authors:
This Research Topic welcomes contributions from researchers across disciplines, including neurology, neuroscience, radiology, pathology, and translational medicine. We invite original research articles, review articles, case studies, and experimental studies that focus on, but are not limited to, the following themes:
• Longitudinal studies investigating the evolution of enlarged perivascular spaces in neurologic diseases
• Molecular and cellular mechanisms underlying the progression and remodeling of EPVS
• Associations between EPVS evolution and neurodegenerative disorders, cerebrovascular diseases, or neuroinflammatory conditions
• Imaging techniques and biomarkers for assessing the evolutionary patterns of EPVS
• Predictive value of EPVS evolution in the diagnosis, prognosis, and monitoring of neurologic diseases
• Therapeutic implications and interventions targeting EPVS progression and related neurologic conditions
By compiling diverse research perspectives, this Research Topic aims to enhance our understanding of the evolution of enlarged perivascular spaces in neurologic diseases and its clinical significance. The exchange of knowledge and collaboration among experts will help elucidate the underlying mechanisms, inform clinical management strategies, and potentially contribute to the development of novel therapeutic interventions for patients affected by these conditions.
Keywords: enlarged perivascular spaces, EPVS, perivascular spaces, neurodegeneration, neuroinflammation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
