About this Research Topic
This research topic aims to explore the diverse biological processes governed by cell communication signaling networks under both normal and pathological conditions. Specifically, the focus is on three key areas: intercellular junctions with barrier functions, cell adhesion molecules that mediate interactions with the extracellular matrix (ECM), and actin-rich protrusions such as podosomes in normal cells and invadopodia in cancer cells. By investigating these areas, the research seeks to answer critical questions about the regulation of cell motility and the role of cell communication in disease progression. The goal is to uncover novel insights that could lead to the identification of potential biomarkers for early tumor detection and the development of more efficient treatment strategies.
To gather further insights into the mechanisms of dynamic cell communications, we welcome articles addressing, but not limited to, the following themes:
- Signaling via cell-cell communication
- Genomic, epigenomic, and proteomic approaches in cell communication research
- Cross-talks of signaling molecules involved in cell motility
- Regulation of podosome formation in healthy cells
- Processes of invadopodia formation in malignant cells
- Molecular profiling of pathogenic cell communications
- Protein-protein interactions regulating cell motility
We encourage the submission of both review papers and original research studies that delve into these aspects of cell-cell communication.
Keywords: cell-cell communication, intercellular junctions, cross-talks of signaling molecules involved in cell motility, podosome, invadosome, invadopodia, genomic/epigenomic/proteomic approaches, protein-protein interactions regulating cell communications
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.