About this Research Topic
Epigenetics of aging and cancer is an important and ever evolving field of study with major implications for medicine. It is well established that epigenetic changes have a significant role in age-associated health disorders as well as in the age-related risk of cancer development. Due to the increasing aging population worldwide, understanding the epigenetic mechanisms of aging and cancer, as well as the implementation of diagnostic approaches, is an important effort with several technological and conceptual advances in recent years. The intersection of these areas offers a wealth of topics for discussion.
The field of epigenetics is rapidly evolving, with new discoveries and technologies continuously being developed. Reviewing current advances in this area can provide a comprehensive overview of the latest findings and methodologies. Exploring epigenetic markers in aging and cancer has direct implications for clinical practice, such as identifying biomarkers for early diagnosis, developing targeted therapies, and exploring potential interventions to mitigate age-related diseases. It is likely there are many opportunities to advance our understanding and further develop therapeutic tools that target age-related vulnerabilities/dependencies of cancers/metastases.
Another aspect to consider is development of preclinical models that take into account age of anima for cancer development and treatment studies. Epigenetic markers, its implications, is essential to consider in such models. This topic spans across various scientific disciplines, encouraging interdisciplinary collaboration and bringing together researchers from genetics, molecular biology, oncology, and aging studies, among others. Therefore, discussing future challenges in this area can inspire further research, highlighting gaps in knowledge, technological limitations, thereby guiding future studies.
This Research Topic welcomes submissions investigating, but not limited to, the following topics:
• Exploring Novel Epigenetic Markers in Aging and Cancer:
• Technological Advancements in Epigenetic Research
• Epigenetic Reprogramming in Cancer Therapeutics
• Epigenetic Clocks and Biomarkers for Aging and Cancer
The field of epigenetics is rapidly evolving, with new discoveries and technologies continuously being developed. Reviewing current advances in this area can provide a comprehensive overview of the latest findings and methodologies. Exploring epigenetic markers in aging and cancer has direct implications for clinical practice, such as identifying biomarkers for early diagnosis, developing targeted therapies, and exploring potential interventions to mitigate age-related diseases. It is likely there are many opportunities to advance our understanding and further develop therapeutic tools that target age-related vulnerabilities/dependencies of cancers/metastases.
Another aspect to consider is development of preclinical models that take into account age of anima for cancer development and treatment studies. Epigenetic markers, its implications, is essential to consider in such models. This topic spans across various scientific disciplines, encouraging interdisciplinary collaboration and bringing together researchers from genetics, molecular biology, oncology, and aging studies, among others. Therefore, discussing future challenges in this area can inspire further research, highlighting gaps in knowledge, technological limitations, thereby guiding future studies.
This Research Topic welcomes submissions investigating, but not limited to, the following topics:
• Exploring Novel Epigenetic Markers in Aging and Cancer:
• Technological Advancements in Epigenetic Research
• Epigenetic Reprogramming in Cancer Therapeutics
• Epigenetic Clocks and Biomarkers for Aging and Cancer
Keywords: Epigenetic Modifications in Aging, Epigenomic Changes in Cancer Development, Chromatin Remodeling During Aging, DNA Methylation Patterns in Aging Cells, Histone Modification Dynamics in Cancer Cells and Epigenetic Landscape of Aging and Cancer
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
