About this Research Topic
Extracellular vesicles (EVs), encompassing both small and large vesicles, are pivotal in mediating intercellular communication, particularly during embryogenesis and morphogenesis. These vesicles are crucial for the temporal and spatial coordination of developmental processes, influencing tissue patterning and stem cell fate decisions. Recent studies have highlighted the role of EVs in epigenetic modulation and their integration with established developmental pathways, underscoring their transformative impact on cellular processes. Despite these advances, significant gaps remain in our understanding of how EVs orchestrate these complex biological events. Current research is increasingly focused on the potential links between embryonic signaling pathways mediated by EVs and cancer progression, suggesting a broader significance of these vesicles beyond development. However, the precise mechanisms by which EVs contribute to these processes, particularly in organ-specific morphogenesis and maternal-fetal communication, remain inadequately explored, necessitating further investigation.
This Research Topic aims to deepen our understanding of EV-mediated cell signaling within the realms of embryonic development and morphogenesis. A primary objective is to elucidate how EVs, especially large and small vesicles, manage the temporal and spatial dynamics essential for embryogenesis. Key questions include how EVs transmit molecular signals during early development, their role in tissue patterning, and their influence on stem cell fate decisions. By addressing these questions, the research seeks to understand the complexities of EV functions and their broader implications in developmental biology and disease.
To gather further insights into the role of EVs in embryogenesis and morphogenesis, we welcome articles addressing, but not limited to, the following themes:
- How EVs identify molecular signals during critical embryonic stages.
- The role of EVs in providing spatial cues for tissue organization during morphogenesis.
- How EVs shape stem cell fate decisions, bridging the gap between embryogenesis and tissue homeostasis in adults.
- The involvement of EVs in epigenetic modifications, contributing to the regulatory landscape of developmental processes.
- The complex interplay between EV signaling and canonical developmental pathways, elucidating synergistic or antagonistic effects.
- The effects of EV contents on cellular processes, illuminating the molecular intricacies driving morphogenesis.
- The roles played by EVs in the formation and development of specific organs during embryogenesis.
- The molecular dialogues facilitated by EVs in the communication between maternal and fetal tissues during embryonic development.
- The influence of EVs, spanning embryonic origins to the intricate network of synaptic connections in neural development.
- Investigate potential connections between embryonic signaling pathways carried by EVs and their role in adulthood cancer progression.
This Research Topic aims to deepen our understanding of EV-mediated cell signaling within the realms of embryonic development and morphogenesis. A primary objective is to elucidate how EVs, especially large and small vesicles, manage the temporal and spatial dynamics essential for embryogenesis. Key questions include how EVs transmit molecular signals during early development, their role in tissue patterning, and their influence on stem cell fate decisions. By addressing these questions, the research seeks to understand the complexities of EV functions and their broader implications in developmental biology and disease.
To gather further insights into the role of EVs in embryogenesis and morphogenesis, we welcome articles addressing, but not limited to, the following themes:
- How EVs identify molecular signals during critical embryonic stages.
- The role of EVs in providing spatial cues for tissue organization during morphogenesis.
- How EVs shape stem cell fate decisions, bridging the gap between embryogenesis and tissue homeostasis in adults.
- The involvement of EVs in epigenetic modifications, contributing to the regulatory landscape of developmental processes.
- The complex interplay between EV signaling and canonical developmental pathways, elucidating synergistic or antagonistic effects.
- The effects of EV contents on cellular processes, illuminating the molecular intricacies driving morphogenesis.
- The roles played by EVs in the formation and development of specific organs during embryogenesis.
- The molecular dialogues facilitated by EVs in the communication between maternal and fetal tissues during embryonic development.
- The influence of EVs, spanning embryonic origins to the intricate network of synaptic connections in neural development.
- Investigate potential connections between embryonic signaling pathways carried by EVs and their role in adulthood cancer progression.
Keywords: Extracellular vesicles, Embryogenesis to Morphogenesis, Embryogenic genes in Cancer
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
