The field of research on long COVID, also known as post-COVID-19 syndrome, has gained significant attention due to the persistent and diverse symptoms experienced by individuals long after the acute phase of SARS-CoV-2 infection. Despite the rapid advancements in understanding the acute infection, long COVID remains a complex and multifaceted condition affecting millions globally. Current literature identifies over 100 potential symptoms, including extreme fatigue, dizziness, insomnia, depression, anxiety, memory and concentration impairments, loss of smell or taste, tinnitus, earaches, chest pain, heart palpitations, tightness, and muscle aches. However, significant gaps persist in the identification, timeframe, mechanisms, and treatment strategies for managing long COVID. Addressing these gaps is crucial for developing effective interventions and improving patient outcomes.

This research topic aims to update the current understanding of long COVID in relation to the underlying mechanisms, classification, and potential treatment approaches. Specifically, it seeks to identify groups of individuals with long COVID based on mechanisms or clinical symptomatology, which could lead to more targeted and effective treatment strategies. By exploring these aspects, the research aims to answer critical questions about the pathophysiology of long COVID, the risk factors contributing to its development, and the most promising therapeutic interventions.

To gather further insights into the complexities of long COVID, we welcome articles addressing, but not limited to, the following themes:
- Pathophysiological mechanisms underlying long COVID
- Identification and classification of long COVID subgroups
- Risk factors contributing to the development of long COVID
- Long-term clinical outcomes and prognosis of long COVID patients
- Innovative treatment strategies and their efficacy
- Impact of vaccination on the incidence and severity of long COVID
- Psychological and neurological aspects of long COVID
- Rehabilitation and management approaches for long COVID patients

By focusing on these themes, this research topic aims to fill the existing knowledge gaps and contribute to the development of comprehensive management strategies for long COVID."

Submit your idea

Impact

Frontiers in Human Neuroscience

Submit your idea

Impact