The intersection of Computational Fluid Dynamics (CFD) with medical science, specifically in otorhinolaryngology and pulmonary medicine, opens up a frontier not only in clinical applications but also in computational advances. CFD's significance in Virtual Endoscopic Sinus Surgery (FESS) and drug delivery systems (both nasal and pulmonary) is undeniable. This technology, rooted in numerical methods to analyze fluid flow in anatomically realistic respiratory pathways, provides detailed insights into the dynamics of air and liquid in complex biological structures. For FESS, CFD delves into airflow dynamics in the nasal cavity, aiding in more precise surgical planning, while in drug delivery, especially with systems like nebulizers, CFD optimizes the distribution and deposition of medication in the respiratory system. As the medical community seeks to enhance patient outcomes with less invasive and more targeted treatments, the integration of CFD presents exciting opportunities for computational advancements.

This Research Topic's primary objective is to confront and navigate the complexities of applying Computational Fluid Dynamics (CFD) to otorhinolaryngology, particularly in Virtual Endoscopic Sinus Surgery (FESS), nasal and oral drug delivery, extending to lung drug delivery systems like nebulizers. The central challenge lies in the pursuit of more precise and effective treatments in these areas, where traditional methodologies often fall short.

Focused on the use of Computational Fluid Dynamics (CFD) in otorhinolaryngology, with a particular emphasis on Virtual Endoscopic Sinus Surgery (FESS), nasal drug delivery, and extension to lung drug delivery systems such as nebulizers, this Research Topic invites contributions that address the following themes:

• Advancements in CFD Modelling: Seeking studies that develop and validate advanced CFD models for sinus surgery, nasal, oral, and lung drug delivery. This includes the creation of detailed models replicating the complex fluid dynamics in these areas, contributing to more accurate and effective computational treatments.

• Innovations in Sinus Surgery and Lung Therapeutics: Submissions detailing the application of CFD in enhancing surgical tools and techniques in FESS, as well as optimizing lung drug delivery methods like nebulizers and inhalers. Papers may focus on how these computational advancements lead to improved patient outcomes and treatment efficacy.

• Optimization of Drug Delivery Systems: Encouraging investigations that use CFD to analyze and improve drug delivery in the nasal cavity, sinuses, and lungs. This includes comparative studies on the computational effectiveness of various delivery methods and the exploration of new technologies for targeted treatment.

• Cross-disciplinary Approaches: Welcoming contributions that integrate CFD with other disciplines such as bioengineering, pharmacology, and material science. These papers should explore how interdisciplinary computational approaches can advance drug delivery systems and computational techniques in surgery.

Original research articles, comprehensive review papers, case studies, and methodological advancements are of interest. Authors are encouraged to present novel findings or practical applications that significantly contribute to the computational advancement of otorhinolaryngology and pulmonary medicine through the lens of computational fluid dynamics.

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Frontiers in Medical Engineering

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