About this Research Topic
Pediatric liver transplantation has evolved into a life-saving intervention for children with end-stage liver disease, acute liver failure, or inborn metabolic disorders. Over the past decade, there has been a notable surge in the number of pediatric liver transplant procedures worldwide. Advances in surgical techniques, immunosuppressive therapies, and donor-recipient matching have collectively contributed to improved outcomes, making transplantation a viable option for a growing number of young patients.
Despite these advancements, challenges persist. The shortage of suitable organs for transplantation remains a significant barrier, prompting innovative strategies such as living donor transplantation and split liver transplantation to expand the donor pool. Additionally, the unique immunological considerations in pediatric recipients demand tailored approaches to immunosuppression, striking a delicate balance between preventing rejection and minimizing adverse effects on growth and development. The field is also witnessing increased attention on long-term outcomes and quality of life for pediatric liver transplant recipients. Understanding the impact of transplantation on growth, neurocognitive development, and psychosocial well-being is crucial for optimizing post-transplant care. As we navigate the current landscape, ongoing research and collaborative efforts are imperative to address these challenges and further enhance the success and sustainability of pediatric liver transplantation.
The proposed Research Topic aims to provide a comprehensive overview of the latest advancements in pediatric liver transplantation, focusing on current trends and future directions in the field. With a particular emphasis on innovative approaches, emerging technologies, and multidisciplinary collaboration, this Research Topic seeks to contribute valuable insights into the ever-evolving landscape of pediatric liver transplantation.
We welcome Original Research articles, Comments, Reviews/ Mini-Reviews, Systematic Reviews, Short Reports, or any other format covering, but not limited to, the following subtopics:
State-of-the-art Techniques in Pediatric Liver Transplantation
Immunological Challenges and Solutions in Pediatric Liver Transplants
Pediatric Liver Transplantation Outcomes: Lessons Learned and Future Considerations
Ethical and Legal Implications in Pediatric Liver Donation and Transplantation
Innovations in Pediatric Liver Preservation and Machine Perfusion
Advancements in Pediatric Living Donor Liver Transplantation
Impact of Genetics on Pediatric Liver Transplantation
Psychosocial Considerations in Pediatric Liver Transplantation: Patient and Family Perspectives
Despite these advancements, challenges persist. The shortage of suitable organs for transplantation remains a significant barrier, prompting innovative strategies such as living donor transplantation and split liver transplantation to expand the donor pool. Additionally, the unique immunological considerations in pediatric recipients demand tailored approaches to immunosuppression, striking a delicate balance between preventing rejection and minimizing adverse effects on growth and development. The field is also witnessing increased attention on long-term outcomes and quality of life for pediatric liver transplant recipients. Understanding the impact of transplantation on growth, neurocognitive development, and psychosocial well-being is crucial for optimizing post-transplant care. As we navigate the current landscape, ongoing research and collaborative efforts are imperative to address these challenges and further enhance the success and sustainability of pediatric liver transplantation.
The proposed Research Topic aims to provide a comprehensive overview of the latest advancements in pediatric liver transplantation, focusing on current trends and future directions in the field. With a particular emphasis on innovative approaches, emerging technologies, and multidisciplinary collaboration, this Research Topic seeks to contribute valuable insights into the ever-evolving landscape of pediatric liver transplantation.
We welcome Original Research articles, Comments, Reviews/ Mini-Reviews, Systematic Reviews, Short Reports, or any other format covering, but not limited to, the following subtopics:
State-of-the-art Techniques in Pediatric Liver Transplantation
Immunological Challenges and Solutions in Pediatric Liver Transplants
Pediatric Liver Transplantation Outcomes: Lessons Learned and Future Considerations
Ethical and Legal Implications in Pediatric Liver Donation and Transplantation
Innovations in Pediatric Liver Preservation and Machine Perfusion
Advancements in Pediatric Living Donor Liver Transplantation
Impact of Genetics on Pediatric Liver Transplantation
Psychosocial Considerations in Pediatric Liver Transplantation: Patient and Family Perspectives
Keywords: pediatrics, liver transplantation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
