In recent years, there has been a significant focus on the development of novel biomaterials and nanomaterials for cancer diagnosis and treatment. These advancements aim to address the limitations of current methods, which often lack satisfactory efficacy. The application of these new biomaterials encompasses various aspects of cancer treatment, including improving tumour-targeting efficacy, reducing side effects, and sensitizing cancer cells to existing treatments. Additionally, researchers are exploring the synthesis of novel nano and biomaterials to develop innovative anti-cancer drugs.

Another crucial area of focus is cancer imaging, where the current systems and contrast agents face challenges in diagnosing small tumours or metastatic colonies. This highlights the need for the development of targeted and tumour-specific contrast agents. Many experts believe that the future of cancer lies in the utilization of nano and biomaterials.

Efficient drug delivery and sustained release at the tumour site are of paramount importance. Researchers are exploring the use of different nano and biomaterials to target cancer cells, enable drug release at the tumour site, and manage hypoxic areas within tumours. Furthermore, due to the unsatisfactory therapeutic effects of current chemotherapy and radiotherapy drugs, there is a growing emphasis on designing novel radiosensitizers, chemosensitizers, and even nano/biomaterials with direct anti-cancer effects.

In-depth investigations through in vitro and in vivo experiments are crucial to understanding various aspects of these nano/biomaterials, such as biocompatibility, biodegradation, cancer toxicity, tumour targeting, and biodistribution.

The goal of the research topic is to explore the potential of novel biomaterials and nanomaterials in improving cancer diagnosis and treatment. The focus is on developing targeted and tumour-specific contrast agents for cancer imaging, as well as utilizing different nano and biomaterials for targeted drug delivery, sustained release at the tumour site, and management of hypoxic sites.

We welcome submissions of the following article types: Mini Review, Original Research, Perspective, and Review. Areas to be covered in this Research Topic may include developed nano/biomaterials but are not limited to:

Biocompatibility
Anti-cancer effects
Anti-metastasis effects
Anti-cancer therapeutic effects in vitro and in vivo
Biodegradation
Tumour targeting efficacy
Biodistribution

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Frontiers in Biomaterials Science

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