Hereditary neuromuscular diseases are a group of inherited disorders affecting motor neurons, peripheral nerves, skeletal muscle, or neuromuscular junctions. Hereditary neuromuscular diseases are recognized as a major cause of death, disability, and mental illness worldwide. For this reason, inherited neuromuscular diseases have become one of the most important public health challenges. since the discovery of the gene for Duchenne muscular dystrophy (DMD) in 1986, remarkable research advances have been made and genetic mutations responsible for the etiology of many inherited neuromuscular diseases have been identified to date.
Biochemical, molecular biological, and animal model studies have elucidated the detailed mechanisms of action of disease-causing genetic mutations. However, there are not always many fundamental treatment options available, and there is an urgent need to develop efficient therapies. Currently, research on the development of efficient and novel therapies for patients with inherited neuromuscular diseases is being intensively pursued.
Stem cells present in animal organs differentiate to become specific cells and are involved in the growth and repair of that organ. Furthermore, stem cells can be used for regenerative therapeutic purposes to regenerate and repair damaged and dysfunctional tissues due to disease or injury.
This Research Topic welcomes original papers, short communications, and review articles that focus on stem cell biology as well as stem cell-based regenerative medicine as a novel therapeutic approach for inherited neuromuscular diseases with the aim to shed light on the underlying biology, applications, and prospects.
A full list of accepted article types, including descriptions, can be found at this link.
Keywords:
stem cells, neuromuscular diseases, inherited diseases, regenerative medicine
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Hereditary neuromuscular diseases are a group of inherited disorders affecting motor neurons, peripheral nerves, skeletal muscle, or neuromuscular junctions. Hereditary neuromuscular diseases are recognized as a major cause of death, disability, and mental illness worldwide. For this reason, inherited neuromuscular diseases have become one of the most important public health challenges. since the discovery of the gene for Duchenne muscular dystrophy (DMD) in 1986, remarkable research advances have been made and genetic mutations responsible for the etiology of many inherited neuromuscular diseases have been identified to date.
Biochemical, molecular biological, and animal model studies have elucidated the detailed mechanisms of action of disease-causing genetic mutations. However, there are not always many fundamental treatment options available, and there is an urgent need to develop efficient therapies. Currently, research on the development of efficient and novel therapies for patients with inherited neuromuscular diseases is being intensively pursued.
Stem cells present in animal organs differentiate to become specific cells and are involved in the growth and repair of that organ. Furthermore, stem cells can be used for regenerative therapeutic purposes to regenerate and repair damaged and dysfunctional tissues due to disease or injury.
This Research Topic welcomes original papers, short communications, and review articles that focus on stem cell biology as well as stem cell-based regenerative medicine as a novel therapeutic approach for inherited neuromuscular diseases with the aim to shed light on the underlying biology, applications, and prospects.
A full list of accepted article types, including descriptions, can be found at this
link.
Keywords:
stem cells, neuromuscular diseases, inherited diseases, regenerative medicine
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.