Bipolar Disorder: Where are we now? Treatment Response, Neural Correlates and Personality

Bipolar disorder is a complex psychiatric condition characterized by fluctuations in mood, energy levels, and cognitive functioning. It is recognized as a bio-psycho-social disorder, with genetic, environmental, and psychological factors influencing its development and course. This Research Topic aims to provide a comprehensive understanding of bipolar disorder by examining various dimensions associated with the disease, including psychosocial, everyday functioning, and cognitive aspects. Exploring markers, neural correlates, and relevant socio-economic factors can enrich our understanding of this disorder and contribute to the refinement of diagnostic and therapeutic approaches.

The goal of this Research Topic is to address the current state of research on bipolar disorder and provide insights into crucial aspects related to its identification, diagnosis, treatment response, and longitudinal course. By examining the bio-psycho-social dimensions of bipolar disorder, we aim to: Evaluate early identification and diagnostic strategies; Investigate the response to existing treatments and explore innovative therapeutic approaches, including new technologies and therapies; Analyze the longitudinal course of bipolar disorder, considering state and trait markers and cognitive functioning; Explore biological and neural correlates associated with the disorder; Examine personality dimensions and socioeconomic variables that influence the manifestation and management of bipolar disorder. By providing a comprehensive overview of current research and exploring potential future developments, this Research Topic aims to foster a deeper understanding of bipolar disorder among clinicians, researchers, and health professionals. This knowledge will contribute to the ongoing refinement of diagnostic and therapeutic approaches, ultimately improving outcomes for individuals with bipolar disorder.

We welcome original research articles, case reports, reviews, and perspectives that shed light on the diverse aspects related to bipolar disorder as a bio-psycho-social disorder. Contributors are encouraged to address the following themes:

• Psychosocial, everyday functioning, and cognitive aspects of bipolar disorder

• Early identification, diagnosis, and assessment strategies

• Treatment response and innovative therapeutic approaches

• Longitudinal course, state and trait markers, and cognitive functioning

• Biological and neural correlates of bipolar disorder

• Influence of personality dimensions and socioeconomic variables on the disorder

Keywords: Bipolar Disorder, Treatment Response, Neural Correlates

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.